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Documenti fondamentali

P0175

Sigma-Aldrich

pGlu-Val-Asn-Phe-Ser-Pro-Gly-Trp-Gly-Thr-NH2

≥95% (HPLC)

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About This Item

Formula empirica (notazione di Hill):
C50H67N13O14
Numero CAS:
Peso molecolare:
1074.15
Numero MDL:
Codice UNSPSC:
12352202
ID PubChem:
NACRES:
NA.26

product name

pGlu-Val-Asn-Phe-Ser-Pro-Gly-Trp-Gly-Thr-NH2, ≥95% (HPLC)

Saggio

≥95% (HPLC)

Forma fisica

powder

Colore

white to off-white

Temperatura di conservazione

−20°C

Stringa SMILE

CC(C)C(NC(=O)C1CCC(=O)N1)C(=O)NC(CC(N)=O)C(=O)NC(Cc2ccccc2)C(=O)NC(CO)C(=O)N3CCCC3C(=O)NCC(=O)NC(Cc4c[nH]c5ccccc45)C(=O)NCC(=O)NC(C(C)O)C(N)=O

InChI

1S/C50H67N13O14/c1-25(2)41(62-45(72)31-15-16-38(67)56-31)49(76)59-34(20-37(51)66)47(74)58-32(18-27-10-5-4-6-11-27)46(73)60-35(24-64)50(77)63-17-9-14-36(63)48(75)55-22-39(68)57-33(19-28-21-53-30-13-8-7-12-29(28)30)44(71)54-23-40(69)61-42(26(3)65)43(52)70/h4-8,10-13,21,25-26,31-36,41-42,53,64-65H,9,14-20,22-24H2,1-3H3,(H2,51,66)(H2,52,70)(H,54,71)(H,55,75)(H,56,67)(H,57,68)(H,58,74)(H,59,76)(H,60,73)(H,61,69)(H,62,72)
NHXHBXCOYZFUSO-UHFFFAOYSA-N

Amino Acid Sequence

Glp-Val-Asn-Phe-Ser-Pro-Gly-Trp-Gly-Thr-NH2

Azioni biochim/fisiol

Hypertrehalosemic neuropeptide from cockroach (Nauphoeta cinerea) with an amino acid sequence similar to that of adipokinetic hormone; involved in carbohydrate metabolism and increases the trehalose content of hemolymph.
Glp-Val-Asn-Phe-Ser-Pro-Gly-Trp-Gly-Thr-NH2 is a hypertrehalosemic neuropeptide (Nauphoeta cinerea) has an amino acid sequence similar to that of adipokinetic hormone and is involved in carbohydrate metabolism and increases the trehalose content of hemolymph.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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G Gäde et al.
General and comparative endocrinology, 86(1), 119-127 (1992-04-01)
Two hypertrehalosemic neuropeptides from the corpus cardiacum of the cockroach Polyphaga aegyptiaca were isolated by reversed-phase high-performance liquid chromatography, and their primary structures were determined by pulsed-liquid phase sequencing employing Edman chemistry, after enzymically deblocking the N-terminal pyroglutamate residue. As
J Y Bradfield et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(10), 4558-4562 (1991-05-15)
Hypertrehalosemic hormone (a carbohydrate-mobilizing neuroendocrine decapeptide) and starvation markedly increased levels of a cockroach (Blaberus discoidalis) fat body cytochrome P450 message. The gene represented by the cloned P450 cDNA has been named CYP4C1 (cytochrome P450 family 4, subfamily C, gene
G Gäde et al.
Biochemical and biophysical research communications, 141(2), 774-781 (1986-12-15)
The hypertrehalosaemic factor from the cockroach Nauphoeta cinerea, a decapeptide, has been assigned the structure >Glu-Val-Asn-Phe-Ser-Pro-Gly-Trp-Gly-Thr-NH2. The structure was assigned from its high-resolution fast atom bombardment mass spectrum and metastable studies on the M + H ion and confirmed by
J Kim et al.
Biochemistry and molecular biology international, 35(4), 803-811 (1995-04-01)
A new method for the determination of the modified amino acid structures of peptides containing pyroglutamyl residue in their N-terminal position is reported. The combination of fast atom bombardment (FAB) mass spectrometry and pyroglutamate aminopeptidase digestion provides a convenient and
Role of Insect Neuropeptides and Juvenile Hormones in Silk Protein Biosynthesis
Unni, B.G. et al.
Annals of Neurology, 15, 112-117 (2008)

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