MAK184
Succinate Colorimetric Assay Kit
Sufficient for 100 Colorimetric tests
Sinonimo/i:
Succinic Acid Assay Kit
Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
About This Item
Prodotti consigliati
applicazioni
cosmetics
food and beverages
Metodo di rivelazione
colorimetric
Malattie correlate
cardiovascular diseases; immunological diseases
Temperatura di conservazione
−20°C
Descrizione generale
Succinate (succinic acid) is a citric acid cycle intermediate and functions in the transport of electrons to the mitochondrial electron transport chain.[1][2] It also functions in innate immune signaling and induces IL-1β production during inflammation. Succinates have been often used for the treatment of hypertension.[3] Succinate measurements can be useful for studying its metabolic, immunological, and therapeutic activities.
Applicazioni
Compatibilità
Suitable for the detection of succinate in a variety of samples such as cell and tissue culture supernatants and in liquid samples such as wine.
Principio
The Succinate Colorimetric Assay Kit is a highly sensitive assay for determining succinate levels (ranging from 2-10 nmole/well) in a variety of samples. Succinate concentration is determined by a coupled enzyme reaction, which results in a colorimetric (450 nm) product proportional to the succinate present.
Solo come componenti del kit
N° Catalogo
Descrizione
- Succinate Assay Buffer
- Succinate Converter
- Succinate Enzyme Mix
- Succinate Substrate Mix
- Succinate Developer
- Succinate Standard
Avvertenze
Danger
Indicazioni di pericolo
Classi di pericolo
Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B
Codice della classe di stoccaggio
8A - Combustible corrosive hazardous materials
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Mengdi Zhang et al.
Cell death discovery, 8(1), 138-138 (2022-03-31)
Hypoxia causes neonatal neuronal damage. However, the underlying mechanism remains unclear. This study aimed to explore the changes in succinate levels and identify the mechanisms underlying their contribution to hypoxia-induced damage in newborn mice. The neonatal C57BL/6J mouse hypoxia model
Electron Transport and Oxidative Phosphorylation
Lodish H, et al.
Molecular Cell Biology (2000)
VSIG4 inhibits proinflammatory macrophage activation by reprogramming mitochondrial pyruvate metabolism.
Li J, et al.
Nature Communications, 8(1), 1322-1322 (2017)
DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism.
Shen J, et al.
JCI insight, 2(12) (2017)
Metoprolol succinate extended release/hydrochlorothiazide combination tablets.
Hainer JW and Jennifer S
Vascular Health, 3(3), 279-279 (2007)
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