MAK106
CETP Activity Assay Kit
Supplied by Roar Biomedical, Inc.
Sinonimo/i:
Cholesteryl ester transfer protein activity assay kit
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About This Item
Codice UNSPSC:
12161503
NACRES:
NA.84
Prodotti consigliati
impiego
sufficient for 100 fluorometric tests
applicazioni
pharmaceutical
Metodo di rivelazione
fluorometric
Malattie correlate
cardiovascular diseases
Temperatura di conservazione
2-8°C
Informazioni sul gene
human ... CETP(1071)
Descrizione generale
Cholesteryl ester transfer protein (CETP) is present in normal human plasma. The protein transfers neutral lipids from high density lipoproteins (HDL) to very low density lipoprotein (VLDL) and low density lipoprotein (LDL). CETP plays an important role in lipoprotein metabolism and influences the reverse cholesterol transport pathway. The method is useful for measuring CETP activity in plasma or serum in all species that express CETP.
Applicazioni
Cholesteryl ester transfer protein (CETP) activity Assay Kit has been used for measurement of CETP activity in the plasma samples.
Caratteristiche e vantaggi
Compatible with high-throughput handling systems.
Compatibilità
Suitable for the detection of cholesteryl ester transfer protein (CETP) in plasma / serum (fresh or frozen), recombinant or purified CETP.
Principio
The CETP Activity Assay Kit uses a proprietary substrate that enables the detection of CETP-mediated transfer of neutral lipid from the substrate to a physiological acceptor. The transfer activity results in an increase in fluorescence intensity (λEx=535 nm/λEm=587 nm). In a total volume of 200 μL, the assay is linear from 0.2 to 0.8 μL of normal human plasma. Assay results not affected by endogenous plasma HDL, LDL or VLDL concentrations.
Risultati analitici
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Codice della classe di stoccaggio
10 - Combustible liquids
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Catherine J McNeal et al.
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Cholesteryl ester transfer protein (CETP) regulates high-density lipoprotein (HDL) cholesterol levels and interaction between glucose, and HDL metabolism is central in the development of diabetes. We hypothesized that CETP levels would be regulated in diabetic pregnancies. We tested the hypothesis
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[Figure: see text].
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