M7397

L-(−)-Malic acid

suitable for cell culture, BioReagent, suitable for insect cell culture

• Sinonimo/i: (S)-(−)-2-Hydroxysuccinic acid, L-Hydroxybutanedioic acid
• Formula condensata: HO₂CCH₂CH(OH)CO₂H
• Numero CAS: 97-67-6
• Peso molecolare: 134.09
• Beilstein: 1723541
• Numero CE: 202-601-5
• Numero MDL: MFCD00064213
• Codice UNSPSC: 12352205
• ID PubChem: 24897161
• NACRES: NA.75

Proprietà

• Origine biologica: microbial
• Nome Commerciale: BioReagent
• Saggio: ≥95% (titration)
• Forma fisica: powder
• tecniche: cell culture | insect: suitable; cell culture | mammalian: suitable
• Punto di fusione: 101-103 °C (lit.)
• Solubilità: water: 100 mg/mL, clear to slightly hazy, colorless
• Stringa SMILE: O[C@@H](CC(O)=O)C(O)=O
• InChI: 1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1; BJEPYKJPYRNKOW-REOHCLBHSA-N

Descrizione

Descrizione generale

Malic acid is used as a component of insect tissue culture. It is also useful as an acidulant in soft drinks, jams, fruit and vegetable juices.

Applicazioni

Malic acid has been used:

• to induce basal respiration in mitochondrial cell culture
• to measure the mitochondrial ETC (electron transport chain) activity
• as a component of mitochondrial substrate stock

Azioni biochim/fisiol

Malic acid is a part of cellular metabolism. Its application is recognized in pharmaceutics. It is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia. It is used as a part of amino acid infusion. Malic acid also serves as a nanomedicine in the treatment of brain neurological disorders. A TCA (Krebs cycle) intermediate and partner in the malic acid aspartate shuttle.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H315,H319
• Consigli di prudenza: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Classi di pericolo: Eye Irrit. 2 - Skin Irrit. 2
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves