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Documenti

L6649

Sigma-Aldrich

Lonomycin A sodium salt from Streptomyces ribosidificus

90-95% (TLC)

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About This Item

Formula empirica (notazione di Hill):
C44H75NaO14
Numero CAS:
58845-80-0
Peso molecolare:
851.05
Beilstein:
4122659
Numero MDL:
MFCD00133488
Codice UNSPSC:
12352200
ID PubChem:
329817642

Saggio

90-95% (TLC)

Temperatura di conservazione

2-8°C

Stringa SMILE

[Na+].CO[C@H]1C[C@]2(CC[C@](C)(O2)[C@H]3CC[C@](C)(O3)[C@@H]4O[C@H]([C@H](OC)[C@@H]4C)[C@H]5O[C@](C)(O)[C@H](C)[C@@H](OC)[C@@H]5C)O[C@@H]([C@@H]1C)[C@@H](C)[C@H]6O[C@](O)([C@H](C)[C@@H](OC)[C@H]6C)[C@H](C)C([O-])=O

InChI

1S/C44H76O14.Na/c1-21-29(49-12)20-43(56-31(21)22(2)32-23(3)34(51-14)27(7)44(48,57-32)28(8)39(45)46)19-18-40(9,58-43)30-16-17-41(10,54-30)38-25(5)35(52-15)37(53-38)36-24(4)33(50-13)26(6)42(11,47)55-36;/h21-38,47-48H,16-20H2,1-15H3,(H,45,46);/q;+1/p-1/t21-,22-,23+,24+,25+,26-,27-,28-,29+,30-,31+,32-,33+,34+,35-,36+,37-,38-,40+,41+,42+,43-,44-;/m1./s1
PIKGYGHAIOUQMF-SZCYNZSUSA-M

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Pittogrammi

Skull and crossbones
GHS06

Avvertenze

Danger

Indicazioni di pericolo

H301 + H311

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 3 Oral

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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[Application of nuclear magnetic resonance to bio-organic chemistry].
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The inhibition of Toxoplasma multiplication inside cells does not correlate with an enhanced release of oxygen intermediates except in the case of peritoneal macrophages treated with Obioactin. The inhibition observed in alveolar macrophages treated with Obioactin, in kidney cells treated
B Marks et al.
Current biology : CB, 8(13), 740-749 (1998-07-04)
Following exocytosis at the synapse, synaptic vesicle components are recovered by endocytosis. Morphological analysis has suggested that this occurs by a clathrin-mediated pathway, and the GTPase dynamin is thought to be involved in 'pinching off' endocytosing vesicles. The finding that
D S Hoover et al.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 8(12), 1371-1380 (1998-01-07)
Expression of Pim-1, an oncogenic serine/threonine kinase, is highly regulated at the transcriptional, posttranscriptional, and posttranslational levels. Here, we report that expression of Pim-1 kinase is additionally regulated at the translational level. Pim-1 protein expression did not increase in Hut-78
M Stoeck et al.
Journal of cellular physiology, 151(1), 8-12 (1992-04-01)
Murine thymocytes were stimulated with the protein kinase C activating agents Phorbol-12-myristate-13-acetate (PMA) or a more physiological membrane permeant diacylglycerol (dioctanoyl-sn-glycerol, DiC8) in the presence or absence of exogenous lymphokines (rIL-1 beta, rIL-2). Whereas PMA directly induced reactivity to rIL-2
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