L2885

Lymphotoxin-β Receptor/Fc Chimera human

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

• Sinonimo/i: TNF R-related protein, TNF RIII
• Numero MDL: MFCD03100005
• Codice UNSPSC: 51111800

Proprietà

• Origine biologica: human
• Ricombinante: expressed in NSO cells
• Saggio: >95% (SDS-PAGE)
• Stato: lyophilized powder
• PM: monomer calculated mol wt 49.6 kDa; 70 kDa by SDS-PAGE (reducing) (due to glycosylation)
• Confezionamento: pkg of 100 μg
• Condizioni di stoccaggio: avoid repeated freeze/thaw cycles
• tecniche: cell culture | mammalian: suitable
• Impurezze: endotoxin, tested
• N° accesso UniProt: P36941
• Temperatura di conservazione: −20°C
• Informazioni sul gene: human ... LTBR(4055)

Descrizione

Azioni biochim/fisiol

LTBR (lymphotoxin β receptor) is a receptor for LIGHT (tumor necrosis factor ligand superfamily member 14) and LT (lymphotoxin)-a1β2. It is present in the epithelial, stromal and myeloid cells. LTBR participates in lymphoid organ development and immune homeostasis. It is also involved in the lipopolysaccharide (LPS)-mediated expression of IL (interleukin)-8.[1]

Stato fisico

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Risultati analitici

The biological activity is measured by the ability of the immobilized LTβR/Fc to bind LTα2/β1 and LTα1/β2 in a functional ELISA.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable