Passa al contenuto
Merck
Tutte le immagini(2)

Documenti

L2262

Sigma-Aldrich

Lipopolysaccharides from Salmonella enterica serotype typhimurium

purified by gel-filtration chromatography

Sinonimo/i:

LPS

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(2)

About This Item

Numero MDL:
MFCD00164404
Codice UNSPSC:
12352201
NACRES:
NA.25

Origine biologica

Salmonella enterica (Serotype typhimurium)

Livello qualitativo

200

Forma fisica

lyophilized powder

Purificato mediante

gel-filtration chromatography

Impurezze

<1% Protein

Colore

white to faint yellow

Solubilità

water: 0.90-1.10 mg/mL, hazy to turbid, colorless to faintly yellow

Condizioni di spedizione

ambient

Temperatura di conservazione

2-8°C

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

This product is extracted from Salmonella typhimurium and purified by gel filtration. The source strain is ATCC 7823.

Applicazioni

Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).

Azioni biochim/fisiol

Lipopolysaccharides (LPS) are localized in the outer layer of the membrane and are, in noncapsulated strains, exposed on the cell surface. They contribute to the integrity of the outer membrane, and protect the cell against the action of bile salts and lipophilic antibiotics.

Nota sulla preparazione

The product is soluble in water (5 mg/ml) or cell culture medium (1 mg/ml) yielding a hazy, faint yellow solution. A more concentrated, though still hazy, solution (20 mg/ml) has been achieved in aqueous saline after vortexing and warming to 70-80 oC. Lipopolysaccharides are molecules that form micelles in every solvent. Hazy solutions are observed in water and phosphate buffered saline. Organic solvents do not give clearer solutions. Methanol yields a turbid suspension with floaters, while water yields a homogeneously hazy solution.

Altre note

To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

L6016

Lipopolysaccharides (rough strains) from Salmonella enterica serotype typhimurium TV119 (Ra mutant)

L7261

Lipopolysaccharides from Salmonella enterica serotype typhimurium, purified by trichloroacetic acid extraction

L6143

Lipopolysaccharides from Salmonella enterica serotype typhimurium, suitable for cell culture, BioXtra, γ-irradiated

L2262

Lipopolysaccharides from Salmonella enterica serotype typhimurium, purified by gel-filtration chromatography

L6511

Lipopolysaccharides from Salmonella enterica serotype typhimurium, purified by phenol extraction

L9516

Lipopolysaccharides (rough strains) from Salmonella enterica serotype typhimurium SL1181

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Rossella Paolillo et al.
International immunopharmacology, 9(11), 1265-1271 (2009-08-04)
Probiotics, defined as live microbial food supplements which improve the health of the host, have obtained increasing medical importance. In the intestine they may prevent the overgrowth of pathogenic bacteria, increase the resistance of the gut to invasion by pathogens
Jia Lin Ren et al.
Scientific reports, 8(1), 429-429 (2018-01-13)
Inflammation is in a wide spectrum of retinal diseases, causing irreversible blindness and visual impairment. We have previously demonstrated that Green Tea Extract (GTE) is a potent anti-inflammatory agent for anterior uveitis. Here we investigated the anti-inflammatory effect of GTE
Barbara Chirullo et al.
Frontiers in microbiology, 6, 985-985 (2015-10-07)
Salmonella Typhimurium (S. Typhimurium) is responsible for foodborne zoonotic infections that, in humans, induce self-limiting gastroenteritis. The aim of this study was to evaluate whether the wild-type strain S. Typhimurium (STM14028) is able to exploit inflammation fostering an active infection.
Varkha Agrawal et al.
Biology of reproduction, 91(5), 119-119 (2014-09-26)
Platelet-activating factor (PAF), a potent phospholipid activator of inflammation that signals through its cognate receptor (platelet-activating factor receptor, PTAFR), has been shown to induce preterm delivery in mice. Toll-like receptors (TLRs) are transmembrane receptors that mediate innate immunity. We have
Andres Gottfried-Blackmore et al.
The Journal of steroid biochemistry and molecular biology, 109(1-2), 96-107 (2008-03-11)
In the CNS, steroid hormones play a major role in the maintenance of brain homeostasis and it's response to injury. Since activated microglia are the pivotal immune cell involved in neurodegeneration, we investigated the possibility that microglia provide a discrete
Visualizza tutti i documenti correlati

Articoli

Lipopolysaccharides for Research – Structure, Function & Applications

Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.

Contenuto correlato

Lipopolysaccharides

Lipopolysaccharide (LPS) is a major component of Gram-negative bacteria, important for microbiological research.

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.