I5161

Iodoacetamide

• Formula condensata: ICH₂CONH₂
• Numero CAS: 144-48-9
• Peso molecolare: 184.96
• EC Number: 205-630-1
• UNSPSC Code: 12352202
• NACRES: NA.21
• Beilstein/REAXYS Number: 1739080
• MDL number: MFCD00008028

Proprietà

• biological source: synthetic
• Quality Segment: 400
• assay: ≥99% (NMR)
• form: powder
• mp: 92-95 °C (lit.)
• solubility: H₂O: 0.5 M, clear, colorless
• suitability: suitable for manufacturing use
• storage temp.: 2-8°C
• SMILES string: NC(=O)CI
• InChI: 1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)
• InChI key: PGLTVOMIXTUURA-UHFFFAOYSA-N

Descrizione

General description

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

Biochem/physiol Actions

Nel sequenziamento dei peptidi, la iodoacetammide agisce come alchilante dei residui di cisteina. È un inibitore irreversibile degli enzimi che presentano residui di cisteina nel sito attivo. Reagisce molto più lentamente con i residui di istidina, ma, benché meno efficace, tale attività è responsabile dell′inibizione della ribonucleasi.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301,H317,H334,H413
• pcodes: P261 - P264 - P273 - P280 - P301 + P310 - P302 + P352
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 4 - Resp. Sens. 1 - Skin Sens. 1
• Classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• flash_point_f: Not applicable
• flash_point_c: Not applicable