I1142
Monoclonal Anti-Interferon-γ antibody produced in rat
clone 37895, purified immunoglobulin, lyophilized powder
Sinonimo/i:
Anti-IFN-γ
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0.5 MG
539,70 €
539,70 €
Prezzo di listino771,00 €Risparmia il 30%Per informazioni sulla disponibilità, contatta il Servizio Clienti.
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Cambia visualizzazione
0.5 MG
539,70 €
About This Item
539,70 €
Prezzo di listino771,00 €Risparmia il 30%Per informazioni sulla disponibilità, contatta il Servizio Clienti.
Prodotti consigliati
Origine biologica
rat
Livello qualitativo
Coniugato
unconjugated
Forma dell’anticorpo
purified immunoglobulin
Tipo di anticorpo
primary antibodies
Clone
37895, monoclonal
Stato
lyophilized powder
Reattività contro le specie
mouse
tecniche
flow cytometry: suitable
neutralization: suitable
western blot: suitable
Isotipo
IgG2a
N° accesso UniProt
Temperatura di conservazione
−20°C
Informazioni sul gene
mouse ... Ifng(15978)
Descrizione generale
Interferon-γ (IFN-γ) belongs to Type II class of interferons and is produced by T helper cells (specifically, Th1 cells), natural killer (NK) and natural killer T (NKT) cells and cytotoxic T cells (TC cells) . It has various biological functions including antiviral activity like inhibition of cell or tumor growth, act as a potent modulator of immune responses and modifies cellular processes as well as stimulates the differentiation of B cells into immunoglobulin-producing cells. Monoclonal Anti-Interferon-γ antibody can be used in immunoblotting. Rat anti-Interferon-γ antibody has shown no cross-reactivity for recombinant human IFN-γ or recombinant rat IFN-γ.
Specificità
The antibody does not cross-react with recombinat human IFN-γ or recombinant rat IFN-γ.
Immunogeno
recombinant mouse IFN-γ.
Applicazioni
Monoclonal Anti-Interferon-γ antibody can be used in neutralization and indirect ELISA.
Stato fisico
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline and 5% trehalose.
Nota sulla preparazione
Purified from cell culture supernatant using protein G.
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Prodotti correlati
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
I Gresser et al.
Proceedings of the National Academy of Sciences of the United States of America, 66(4), 1052-1058 (1970-08-01)
Mouse interferon preparations inhibited the multiplication of mouse leukemia L 1210 cells in stationary suspension cultures. The degree of inhibition was found to correlate with the antiviral titer of the interferon preparations. The factor(s) responsible for inhibition of L 1210
P B Fisher et al.
Pharmacology & therapeutics, 27(2), 143-166 (1985-01-01)
As described in this review, both partially purified and recombinant interferons are potent modulators of differentiation in diverse cell culture systems (Table 2). Depending on the target cell, interferon exerts either an inhibitory or an inductive effect on cell differentiation.
J Vilcek et al.
Journal of immunology (Baltimore, Md. : 1950), 135(3), 1851-1856 (1985-09-01)
Interferon (IFN)-gamma production, stimulated by the addition of exogenous interleukin (IL) 2, T cell mitogens, or tuberculin purified protein derivative (PPD) was studied in cultures of separated human mononuclear cells or unseparated peripheral blood leukocytes (PBL). IFN-gamma was induced by
P D Benech et al.
The Journal of experimental medicine, 176(4), 1115-1123 (1992-10-01)
The human Fc gamma RI (CD64) is a high affinity receptor for the Fc portion of immunoglobulin (Ig), and its constitutively low expression on the cell surface of monocyte/macrophage and neutrophils is selectively upregulated by interferon gamma (IFN-gamma) treatment (Perussia
Jamie R Schoenborn et al.
Advances in immunology, 96, 41-101 (2007-11-06)
Interferon-gamma (IFN-gamma) is crucial for immunity against intracellular pathogens and for tumor control. However, aberrant IFN-gamma expression has been associated with a number of autoinflammatory and autoimmune diseases. This cytokine is produced predominantly by natural killer (NK) and natural killer
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