G1049
Poly-L-γ-glutamic acid sodium salt
suitable for drug transporter assays, Mol wt ≥750,000
Sinonimo/i:
γ-PGA
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About This Item
Prodotti consigliati
product name
Poly-L-γ-glutamic acid sodium salt,
Forma fisica
powder
PM
≥750,000
tecniche
drug transporter assay: suitable
Colore
white to off-white
applicazioni
cell analysis
Temperatura di conservazione
−20°C
Applicazioni
High molecular weight poly-γ-glutamic acid (γPGA) was found to increase levels of NK cell-mediated cytotoxicity and INF-γ secretion in C57BL/6 mice. Biodegradable γ-PGA nanoparticles have been evaluated for use as antigen delivery carriers and delivery of influenza virus hemagglutin (HA) vaccine. Additional life science applications for γ-PGA include uses in biodegradable fibers and nanofiber sheets, hydrogels, and cryoprotectants.
Altre note
High molecular weight poly-γ-glutamic acid is a polymer of glutamic acid connected by amide linkages between α-amino and γ-carboxylic acid groups. γ-PGA is produced by fermentation in Bacillus species. The subunits are predominantly L-isomer.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
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I clienti hanno visto anche
Preparation and evaluation of poly(γ-glutamic acid)-based anti-adhesion membranes.
Kim, Y.-A., et al.
Key Engineering Materials, 342, 225-225 (2007)
The utility of poly(γ-glutamic acid) nanoparticles as antigen delivery carriers in dendritic cell-based cancer immunotherapy.
Matsuo, K., et al.
Biological & Pharmaceutical Bulletin, 33, 2007-2007 (2010)
Shigefumi Okamoto et al.
Vaccine, 27(42), 5896-5905 (2009-08-04)
Adding poly(gamma-glutamic acid) nano-particles (gamma-PGA-NPs), a safe, natural material, to subcutaneous immunization with influenza virus hemagglutinin (HA) vaccine increases the protective immune responses against influenza virus in mice. Here, we examined whether intranasal administration of the HA vaccine with gamma-PGA-NPs
Ilaria Massaiu et al.
Microbial cell factories, 18(1), 3-3 (2019-01-11)
Genome-scale metabolic models (GEMs) allow predicting metabolic phenotypes from limited data on uptake and secretion fluxes by defining the space of all the feasible solutions and excluding physio-chemically and biologically unfeasible behaviors. The integration of additional biological information in genome-scale models
Tae Woo Kim et al.
Journal of immunology (Baltimore, Md. : 1950), 179(2), 775-780 (2007-07-10)
We analyzed the in vivo tumor regression activity of high molecular mass poly-gamma-glutamate (gamma-PGA) from Bacillus subtilis sups. chungkookjang. C57BL/6 mice were orally administered 10-, 100-, or 2000-kDa gamma-PGA or beta-glucan (positive control), and antitumor immunity was examined. Our results
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