Passa al contenuto
Merck
Tutte le immagini(1)

Documenti fondamentali

Visualizza tutta la documentazione

F5307

Sigma-Aldrich

5−Fluoro−2′−deoxycytidine

≥98% (HPLC), powder

Sinonimo/i:

2′-deoxy-5-fluoro-Cytidine, FCDR, FdCyd

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali

Scegli un formato

5 MG
65,45 €
25 MG
364,00 €

65,45 €

Prezzo di listino93,50 €Risparmia il 30%
Per informazioni sulla disponibilità, contatta il Servizio Clienti.
Richiedi un ordine bulk
Tutte le immagini(1)

Scegli un formato

Cambia visualizzazione
5 MG
65,45 €
25 MG
364,00 €

About This Item

Formula empirica (notazione di Hill):
C9H12FN3O4
Numero CAS:
10356-76-0
Peso molecolare:
245.21
Numero MDL:
MFCD00077348
Codice UNSPSC:
12352200
ID PubChem:
329799711
NACRES:
NA.77

65,45 €

Prezzo di listino93,50 €Risparmia il 30%
Per informazioni sulla disponibilità, contatta il Servizio Clienti.
Richiedi un ordine bulk

Saggio

≥98% (HPLC)

Stato

powder

Colore

white to off-white

Solubilità

DMSO: >20 mg/mL

Temperatura di conservazione

room temp

Stringa SMILE

NC1=NC(=O)N(C=C1F)[C@H]2C[C@H](O)[C@@H](CO)O2

InChI

1S/C9H12FN3O4/c10-4-2-13(9(16)12-8(4)11)7-1-5(15)6(3-14)17-7/h2,5-7,14-15H,1,3H2,(H2,11,12,16)/t5-,6+,7+/m0/s1
IDYKCXHJJGMAEV-RRKCRQDMSA-N

Azioni biochim/fisiol

5-Fluoro-2′-deoxycytidine is a mechanism based DNMT (DNA cytosine-5 methyltransferase) inhibitor, that forms a covalent link with the cysteine residue in the active site of DNMT.

Caratteristiche e vantaggi

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
059K4720V
059K47201
059K4720

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 5

1 of 5

Capecitabine ≥98% (HPLC)

Sigma-Aldrich

SML0653

Capecitabine

5-Aza-2′-deoxycytidine ≥97%

Sigma-Aldrich

A3656

5-Aza-2′-deoxycytidine

10058-F4 ≥98% (HPLC), solid

Sigma-Aldrich

F3680

10058-F4

Digoxigenin analytical standard

Supelco

D9026

Digoxigenin

Gemcitabine hydrochloride ≥98% (HPLC)

Sigma-Aldrich

G6423

Gemcitabine hydrochloride

E Harrer et al.
The Journal of infectious diseases, 173(2), 476-479 (1996-02-01)
The human immunodeficiency virus (HIV) type 1 reverse transcriptase (RT) is an important target for therapeutic intervention and for HIV-1-specific cytotoxic T lymphocytes (CTL). An HLA-A2-restricted CTL epitope containing the sequence YMDD, which is highly conserved among human and animal
K M Reinisch et al.
Journal of molecular biology, 238(4), 626-629 (1994-05-13)
A DNA (cytosine)-5-methyltransferase from Haemophilus aegyptius (M.Hae III), which catalyzes methyl transfer from S-adenosyl-L-methionine to DNA, has been crystallized as a covalent complex with a suicide oligonucleotide substrate. Crystals of the co-complex were grown by vapor diffusion with hanging droplets
T Hanck et al.
Nucleic acids research, 21(2), 303-309 (1993-01-25)
The product of the dcm gene is the only DNA cytosine-C5 methyltransferase of Escherichia coli K-12; it catalyses transfer of a methyl group from S-adenosyl methionine (SAM) to the C-5 position of the inner cytosine residue of the cognate sequence
J C Shen et al.
Nucleic acids research, 23(21), 4275-4282 (1995-11-11)
DNA (cytosine-5)-methyltransferases can cause deamination of cytosine when the cofactor S-adenosylmethionine (AdoMet) is limiting and thus function as sequence-specific C-->U mutator enzymes. Here we explored whether mutations causing inactivation of the cofactor binding activity of the HpaII methyltransferase, thus mimicking
M Iigo et al.
Cancer chemotherapy and pharmacology, 20(1), 1-4 (1987-01-01)
The plasma concentration of 5-fluorouracil (FUra) following the i.v. administration of FUra and guanosine 5'-monophosphate (GMP) or guanosine 5'-triphosphate (GTP) was markedly elevated. These values were more than 5-fold higher than those obtained with FUra alone over 60 min after
Visualizza tutti i documenti correlati

Articoli

Discover Bioactive Small Molecules for Gene Regulation

We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

Domande

Recensioni

Nessuna valutazione

Filtri attivi

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.