D8668

2′-Deoxyadenosine monohydrate

powder, BioReagent, suitable for cell culture

• Sinonimo/i: 9-(2-Deoxy-β-D-ribofuranosyl)adenine, Adenine deoxyriboside
• Formula empirica (notazione di Hill): C₁₀H₁₃N₅O₃ · H₂O
• Numero CAS: 16373-93-6
• Peso molecolare: 269.26
• Beilstein: 91015
• Numero CE: 213-488-7
• Numero MDL: MFCD00005754
• Codice UNSPSC: 12352207
• ID PubChem: 24894112
• NACRES: NA.75

Proprietà

• Origine biologica: synthetic (organic)
• Livello qualitativo: 200
• Nome Commerciale: BioReagent
• Saggio: ≥99% (HPLC)
• Forma fisica: powder
• tecniche: cell culture | mammalian: suitable
• Solubilità: H₂O: soluble 25 mg/mL, clear to slightly hazy, colorless to faintly yellow
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: [H]O[H].Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](CO)O3
• InChI: 1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1; OLXZPDWKRNYJJZ-RRKCRQDMSA-N

Descrizione

Applicazioni

2′-Deoxyadenosine monohydrate has been used as a nucleotide precursor:

• To study the importance of homologous recombination at the interface between replication and mitosis
• To analyze deoxynucleoside-assisted transductions
• To study the effect of increased deoxycytidine on gemcitabine resistance in pancreatic cancer cells

2′-Deoxyadenosine monohydrate has been used for the preparation of deoxyribonucleoside stock solution for the anaerobic culture of Bacillus mojavensis strains including JF-2 and two Bacillus subtilis strains.

Azioni biochim/fisiol

Excess 2′-deoxyadenosine gets converted to adenosine triphosphate (dATP), which inhibits ribonucleotide reductase.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Faceshields, Gloves