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C4431

Sigma-Aldrich

Citrate-phosphate-dextrose solution with adenine

Sinonimo/i:

CPD-A

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50 ML
62,50 €
10 X 50 ML
408,00 €

62,50 €

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50 ML
62,50 €
10 X 50 ML
408,00 €

About This Item

Codice UNSPSC:
12161700
NACRES:
NA.25

62,50 €

Per informazioni sulla disponibilità, contatta il Servizio Clienti.
Richiedi un ordine bulk

Sterilità

sterile-filtered

Livello qualitativo

200

Stato

liquid

pH

5.4-6.7

Temperatura di conservazione

2-8°C

Categorie correlate

Descrizione generale

Citrate-phosphate-dextrose solution with adenine (CPDA) is an anticoagulant and preservative for storage of blood. It can prolong red blood cell storage life up to 35 days. It maintains platelet viability.[1] Usage of CPDA improves post-transfusion visibility and improves glucose and ATP levels in blood.[2]

Applicazioni

Citrate-phosphate-dextrose solution with adenine has been used as an anticoagulant during blood collection from cardiac puncture,[3] transgenic hen egg lysozyme-ovalbumin-Duffy (HOD) mice[4] and humans.[5]

Azioni biochim/fisiol

Useful anticoagulant for whole blood
Recommended anticoagulant: whole blood ratio is 1:9

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08168

Timestrip Plus™ 8 °C

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
0000421395
0000421395
0000387191
0000346907
0000362204

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HyunJoo Park et al.
Scientific reports, 6, 34257-34257 (2016-10-05)
The functionality and viability of stored human red blood cells (RBCs) is an important clinical issue in transfusions. To systematically investigate changes in stored whole blood, the hematological properties of individual RBCs were quantified in blood samples stored for various
Krishnan MohanKumar et al.
Nature communications, 10(1), 3494-3494 (2019-08-04)
Necrotizing enterocolitis (NEC) is an idiopathic, inflammatory bowel necrosis of premature infants. Clinical studies have linked NEC with antecedent red blood cell (RBC) transfusions, but the underlying mechanisms are unclear. Here we report a neonatal murine model to investigate this
The storage of hard-packed red blood cells in citrate-phosphate-dextrose (CPD) and CPD-adenine (CPDA-1)
Beutler E and West C
Blood, 54(1), 280-284 (1979)
James C Keith et al.
Arthritis research & therapy, 7(4), R769-R776 (2005-07-01)
The human leukocyte antigen B27 (HLA-B27) transgenic rat is a model of human inflammatory bowel disease, rheumatoid arthritis and psoriasis. Studies of chronic inflammation in other rat models have demonstrated activation of the kallikrein-kinin system as well as modulation by
A monoclonal antibody against kininogen reduces inflammation in the HLA-B27 transgenic rat
Keith JC, et al.
Arthritis Research & Therapy, 7(4), R769-R769 (2005)
Visualizza tutti i documenti correlati

Domande

1–2 di 2 domande  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 risposta

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Utile?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 risposta

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Utile?

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