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C4187

Cyanoborohydride Coupling Buffer

Sinonimo/i:

Coupling buffer

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Voi/SKUDisponibilitàPrezzo
500 mL
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308,00 €

Informazioni su questo articolo

NACRES:
NA.56
UNSPSC Code:
12161700

308,00 €

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form

liquid

Quality Segment

reaction suitability

reagent type: reductant

technique(s)

affinity chromatography: suitable

application(s)

life science and biopharma

storage temp.

2-8°C

Application

A ready-to-use reagent used to couple amine ligands to aldehyde functional groups. The coupling buffer reaction is a reductive amination of the intermediate Schiff′s base to a stable C−N bond.
Cyanoborohydride Coupling Buffer is used in affinity chromatography, protein chromatography, activated/functionalized matrices and synthetic reagents. Cyanoborohydride has been used to inform a safe and effective gene-transfer system targeting hepatocytes as well as to develop a method for targeted delivery of anticancer therapeutics to cancer cells in hypoxic areas.
Cyanoborohydride Coupling Buffer has been used:
  • in coupling reactions between amines and glutaraldehyde
  • to reduce hydrazone bond to a stable hydrazide bond
  • as a component in oligonucleotide reaction mixture for coverslips functionalization

Biochem/physiol Actions

Cyanoborohydride Coupling Buffer is a reagent suitable for reductive amination processes, that contributes to transformation of simple alcohols into more complex amines. It is used in the conversion of Schiff base, by reducing it, to form a secondary amine without affecting aldehyde groups on the support.

Preparation Note

0.02 M sodium phosphate, pH 7.5, containing 0.2 M sodium chloride and 3.0 g/L sodium cyanoborohydride

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Questo articolo
67493152630485810
Cyanoborohydride Coupling Buffer

Sigma-Aldrich

C4187

Cyanoborohydride Coupling Buffer

Cyanoborohydride, silica-supported

Sigma-Aldrich

674931

Cyanoborohydride, silica-supported

Cyanoborohydride, polymer supported macroporous, 20-50 mesh, extent of labeling: ~2.0-3.5 mmol/g loading

Sigma-Aldrich

526304

Cyanoborohydride, polymer supported

STE buffer solution BioUltra, Molecular Biology, pH 7.8

Sigma-Aldrich

85810

STE buffer solution

description

-

description

-

description

macroporous, 20-50 mesh, extent of labeling: ~2.0-3.5 mmol/g loading

description

BioUltra, Molecular Biology, pH 7.8

technique(s)

affinity chromatography: suitable

technique(s)

-

technique(s)

-

technique(s)

-

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

form

liquid

form

-

form

macroporous

form

liquid

application(s)

life science and biopharma

application(s)

-

application(s)

-

application(s)

-

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

-

reaction suitability

reagent type: reductant

reaction suitability

reaction type: solution phase peptide synthesis, reactivity: imine reactive

reaction suitability

reactivity: imine reactive, reaction type: solution phase peptide synthesis

reaction suitability

-

Pittogrammi

Exclamation markEnvironment
GHS07,GHS09

Parola di avvertenza

Warning

Codici di pericolo

H302 + H312,H411

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2

Classe di stoccaggio

12 - Non Combustible Liquids

Punto di infiammabilità (°F)

Not applicable

Punto di infiammabilità (°C)

Not applicable

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