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Merck
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Documenti fondamentali

B9684

Sigma-Aldrich

Anti-Brn3a antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Sinonimo/i:

Anti-FLJ13449, Anti-OCT-T1, Anti-RDC1

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About This Item

Numero MDL:
MFCD02262629
Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

200

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Stato

buffered aqueous solution

PM

antigen 42.9 kDa

Reattività contro le specie

human

Reattività contro le specie (prevista in base all’omologia)

mouse

tecniche

immunocytochemistry: 1:200-1:1000
immunohistochemistry (frozen sections): 1:200-1:1000
western blot: 1:200-1:1000

N° accesso UniProt

Q01851

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... POU4F1(5457)
mouse ... Pou4f1(18996)
rat ... Pou4f1(114503)

Descrizione generale

Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons.

Immunogeno

POU4F1 / BRN3A antibody was raised against synthetic peptide (aa 141-157, AGGGGAHDGPGGGGGPG) corresponding to human Brn3a (BSA conjugated). Percent identity by BLAST analysis: Human (100%); Mouse (94%); Drosophila (82%).

Epitope
aa141-157

Stato fisico

Supplied in phosphate buffered saline, pH 7.4

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Raccomandato

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
SLBT5525
SLBT4491
SLBT1454
SLBS1543V
SLBQ0081V

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Brenna Krieger et al.
PloS one, 12(7), e0180091-e0180091 (2017-07-29)
The retina communicates with the brain using ≥30 parallel channels, each carried by axons of distinct types of retinal ganglion cells. In every mammalian retina one finds so-called "alpha" ganglion cells (αRGCs), identified by their large cell bodies, stout axons
Peter Stacey et al.
SLAS discovery : advancing life sciences R & D, 23(6), 585-596 (2018-03-17)
Screening against a disease-relevant phenotype to identify compounds that change the outcome of biological pathways, rather than just the activity of specific targets, offers an alternative approach to find modulators of disease characteristics. However, in pain research, use of in
RAGE and its ligand amyloid beta promote retinal ganglion cell loss following ischemia-reperfusion injury.
Seyed Hosseini Fin, et al.
Frontiers in Cellular Neuroscience, 17, 1156084-1156084 (2023)
Fuxin Shi et al.
The European journal of neuroscience, 26(11), 3016-3023 (2007-11-17)
In mammals, hair cells and auditory neurons lack the capacity to regenerate, and damage to either cell type can result in hearing loss. Replacement cells for regeneration could potentially be made by directed differentiation of human embryonic stem (hES) cells.
Hans Jürgen Wester et al.
Theranostics, 5(6), 618-630 (2015-04-01)
Chemokine ligand-receptor interactions play a pivotal role in cell attraction and cellular trafficking, both in normal tissue homeostasis and in disease. In cancer, chemokine receptor-4 (CXCR4) expression is an adverse prognostic factor. Early clinical studies suggest that targeting CXCR4 with

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