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Y0001048

Levodropropizine impurity C

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

(±)-Glycidol, (±)-Oxirane-2-methanol, 2,3-Epoxy-1-propanol, Glycerolglycide

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About This Item

Formula empirica (notazione di Hill):
C3H6O2
Numero CAS:
556-52-5
Peso molecolare:
74.08
Beilstein:
383562
Numero MDL:
MFCD00005147
Codice UNSPSC:
41116107
ID PubChem:
329831237
NACRES:
NA.24

Grado

pharmaceutical primary standard

Densità del vapore

2.15 (vs air)

Tensione di vapore

0.9 mmHg ( 25 °C)

Famiglia di API

levodropropizine

Temp. autoaccensione

780 °F

Produttore/marchio commerciale

EDQM

Indice di rifrazione

n20/D 1.433 (lit.)

P. eboll.

61-62 °C/15 mmHg (lit.)

Densità

1.117 g/mL at 25 °C (lit.)

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

−20°C

Stringa SMILE

OCC1CO1

InChI

1S/C3H6O2/c4-1-3-2-5-3/h3-4H,1-2H2
CTKINSOISVBQLD-UHFFFAOYSA-N

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Levodropropizine impurity C EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Classi di pericolo

Acute Tox. 2 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

161.6 °F

Punto d’infiammabilità (°C)

72 °C

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Certificati d'analisi (COA)

Lot/Batch Number

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Glycidol.
IARC monographs on the evaluation of carcinogenic risks to humans, 77, 469-486 (2000-12-02)
Hirotoshi Akane et al.
Journal of applied toxicology : JAT, 34(12), 1389-1399 (2014-01-08)
We previously found that exposure to glycidol at 1000 ppm in drinking water caused axonopathy in maternal rats and aberrations in late-stage hippocampal neurogenesis, targeting the process of neurite extension in offspring. To identify the profile of developmental neurotoxicity of
Kunio Wada et al.
Mutation research. Genetic toxicology and environmental mutagenesis, 769, 1-6 (2014-10-26)
The in vivo comet assay has been used for the evaluation of DNA damage and repair in various tissues of rodents. However, it can give false-positive results due to non-specific DNA damage associated with cell death. In this study, we
Hirotoshi Akane et al.
Toxicology and applied pharmacology, 279(2), 150-162 (2014-06-11)
We previously found that the 28-day oral toxicity study of glycidol at 200mg/kg/day in rats resulted in axonopathy in both the central and peripheral nervous systems and aberrations in the late-stage of hippocampal neurogenesis targeting the process of neurite extension.
B D Craft et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 30(1), 46-51 (2012-10-02)
Recently, fatty acid esters of monochloropropanediol (MCPD) and that of glycidol have been reported in refined edible oils. Since then a wealth of research has been published on the factors influencing the formation of these contaminants in foods. It can
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