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T4764

Supelco

Δ9-Tetrahydrocannabinol solution

1.0 mg/mL in methanol, analytical standard, for drug analysis

Sinonimo/i:

Δ1-Tetrahydrocannabinol

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About This Item

Formula empirica (notazione di Hill):
C21H30O2
Numero CAS:
1972-08-3
Peso molecolare:
314.46
Numero CE:
200-659-6
Numero MDL:
MFCD00083207
Codice UNSPSC:
41116107
ID PubChem:
329826800
NACRES:
NA.24

Grado

analytical standard, for drug analysis

Livello qualitativo

200

drug control

Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

Concentrazione

1.0 mg/mL in methanol

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

pharmaceutical (small molecule)

Formato

single component solution

Temperatura di conservazione

2-8°C

Stringa SMILE

[H][C@@]12CCC(C)=C[C@@]1([H])c3c(O)cc(CCCCC)cc3OC2(C)C

InChI

1S/C21H30O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h11-13,16-17,22H,5-10H2,1-4H3/t16-,17-/m1/s1
CYQFCXCEBYINGO-IAGOWNOFSA-N

Informazioni sul gene

human ... CNR1(1268) , CNR2(1269)
mouse ... Cnr1(12801)
rat ... Cnr1(25248)

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Categorie correlate

Descrizione generale

Δ9-Tetrahydrocannabinol, known as THC, is a C21 terpenophenolic compound and is the primary psychoactive cannabinoid present in cannabis and hemp.

Applicazioni

The Δ9-Tetrahydrocannabinol analytical standard can be used as follows:
  • Development and validation of a high-performance liquid chromatographic method coupled with UV detection to measure cannabidiol and ∆9-tetrahydrocannabinol in rat plasma samples following their extraction by protein precipitation and liquid-liquid extraction (LLE)
  • Estimation of cannabidiol and ∆9-tetrahydrocannabinol extracted from human plasma samples by liquid-liquid extraction using ultra-performance liquid chromatography with triple quadrupole mass spectrometry
  • Multi-residue analysis of Δ9-tetrahydrocannabinol (THC) and its two degradation products, 11-hydroxy-Δ9-tetrahydrocannabinol and 11-nor-9-carboxy-Δ9-tetrahydrocannabinol, in whole blood samples by QuEChERS extraction and gas chromatography (GC) coupled with tandem mass spectrometry (MS/MS)
  • Optimization of an ultra-high performance supercritical fluid chromatographic (UHPSFC) method, combined with a tandem mass spectrometer (MS/MS) to determine ∆9-tetrahydrocannabinol, along with three of its major metabolites and four synthetic metabolites in wastewater samples following liquid-liquid extraction
  • Development and validation of an ultra high-performance liquid chromatographic (UHPLC) method coupled to photodiode array and mass spectrometry detectors to determine 11 cannabinoids in various Cannabis Sativa samples

Altre note

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Avvertenze

Danger

Indicazioni di pericolo

H225,H301 + H311 + H331,H370

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organi bersaglio

Eyes,Central nervous system

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

49.5 °F - closed cup

Punto d’infiammabilità (°C)

9.7 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Elenchi normativi

Forniamo informazioni su eventuali restrizioni prevalentemente per i prodotti chimici. Per altre tipologie di prodotto siamo in grado di fornire soltanto informazioni limitate. Nessuna segnalazione significa che nessuno dei componenti è citato in un elenco. È dovere dell’utilizzatore assicurarsi che il prodotto venga impiegato in maniera sicura e a norme di legge.

EU REACH Annex XVII (Restriction List)

CAS No.

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
0000271055
0000271055
SLCH6733
SLCD5109
SLBZ6905

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M Waldman et al.
Biochemical pharmacology, 85(11), 1626-1633 (2013-03-30)
Tetrahydrocannabinol (THC), the major psychoactive component of marijuana, is a cannabinoid agonist that exerts its effects by activating at least two specific receptors (CB1 and CB2) that belong to the seven transmembrane G-protein coupled receptor (GPCR) family. Both CB1 and
Suspected dronabinol withdrawal in an elderly cannabis-naive medically ill patient.
Russ S Muramatsu et al.
The American journal of psychiatry, 170(7), 804-804 (2013-07-04)
David R Maguire et al.
The Journal of pharmacology and experimental therapeutics, 345(3), 354-362 (2013-03-29)
Cannabinoid receptor agonists enhance the antinociceptive effects of μ-opioid receptor agonists, which suggests that combinations of these drugs might enhance therapeutic effectiveness (e.g., analgesia). However, it is not clear whether combinations of these drugs also enhance abuse or dependence liability.
Z K Krowicki
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 63(6), 581-588 (2013-02-08)
We previously reported that delta-9-tetrahydrocannabinol (delta-9-THC), the primary psychoactive constituent of Cannabis sativa, inhibited gastric motor activity and evoked bradycardia and hypotension upon its parenteral administration in the rat. As prostanoids are important mediators of the actions of cannabinoids, we
Li-Jie Cheng et al.
Organic letters, 15(4), 764-767 (2013-01-26)
The highly efficient asymmetric total syntheses of (-)-Δ(8)-tetrahydrocannabinol ((-)-Δ(8)-THC) (13 steps, 35%) and (-)-Δ(9)-tetrahydrocannabinol ((-)-Δ(9)-THC) (14 steps, 30%) have been developed by using ruthenium-catalyzed asymmetric hydrogenation of racemic α-aryl cyclic ketones via dynamic kinetic resolution and intramolecular S(N)Ar cyclization.
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