PHR1597
CMIT/MIT
Pharmaceutical Secondary Standard; Certified Reference Material
Sinonimo/i:
5-chloro-2-methyl-2h-isothiazolin-3-one/2-methyl-2h-isothiazol-3-one
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About This Item
Codice UNSPSC:
41116107
NACRES:
NA.24
Prodotti consigliati
Grado
certified reference material
pharmaceutical secondary standard
Livello qualitativo
Famiglia di API
cmit/mit
Forma fisica
liquid
CdA
current certificate can be downloaded
Confezionamento
ampule of 1 mL
applicazioni
pharmaceutical (small molecule)
Temperatura di conservazione
2-30°C
Descrizione generale
Pharmaceutical secondary standard for applications in quality control, provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
CMIT/MIT is an isothiazolone biocide having a 3:1 ratio of CMIT and MIT, widely used for its broad-spectrum action against microbes, algae, and fungi. It is one of the active ingredients of humidifier disinfectants and a commonly used preservative in industrial products such as cosmetics, paints, adhesives and detergents.
CMIT/MIT is an isothiazolone biocide having a 3:1 ratio of CMIT and MIT, widely used for its broad-spectrum action against microbes, algae, and fungi. It is one of the active ingredients of humidifier disinfectants and a commonly used preservative in industrial products such as cosmetics, paints, adhesives and detergents.
Applicazioni
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Risultati analitici
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Altre note
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
Codice della classe di stoccaggio
12 - Non Combustible Liquids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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I clienti hanno visto anche
Refined exposure assessment for three active ingredients of humidifier disinfectants
Lee JH, et al.
Environmental Engineering Research, 18(4), 253-257 (2013)
The mechanism of action of isothiazolone biocides
Williams TM
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CMIT/MIT induce apoptosis and inflammation in alveolar epithelial cells through p38/JNK/ERK1/2 signaling pathway
Lee J, et al.
Molecular & Cellular Toxicology, 15(1), 41-48 (2019)
Fatal misuse of humidifier disinfectants in Korea: importance of screening risk assessment and implications for management of chemicals in consumer products
Lee JH, et al.
PowerPlant Chemistry, 9(1), 14-14 (2012)
Risk Assessment of 5-Chloro-2-Methylisothiazol-3 (2H)-One/2-Methylisothiazol-3 (2H)-One (CMIT/MIT) Used as a Preservative in Cosmetics
Kim MK, et al.
Toxicological Research, 35(2), 103-103 (2019)
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