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PHR1229

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Ethylbenzene

Pharmaceutical Secondary Standard; Certified Reference Material

Sinonimo/i:

Ethylbenzene, NSC 406903, Phenylethane

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About This Item

Formula condensata:
C6H5C2H5
Numero CAS:
Peso molecolare:
106.17
Beilstein:
1901871
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

certified reference material
pharmaceutical secondary standard

Livello qualitativo

agenzia

traceable to USP 1265457

Densità del vapore

3.7 (vs air)

Tensione di vapore

10 mmHg ( 20 °C)
19 mmHg ( 37.7 °C)

CdA

current certificate can be downloaded

Temp. autoaccensione

810 °F

Limite di esplosione

6.7 %

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Indice di rifrazione

n20/D 1.495 (lit.)

P. eboll.

136 °C (lit.)

Punto di fusione

−95 °C (lit.)

Densità

0.867 g/mL at 25 °C (lit.)

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-30°C

Stringa SMILE

CCc1ccccc1

InChI

1S/C8H10/c1-2-8-6-4-3-5-7-8/h3-7H,2H2,1H3
YNQLUTRBYVCPMQ-UHFFFAOYSA-N

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Descrizione generale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards..

Applicazioni

Ethylbenzene may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAC3557 in the slot below. This is an example certificate only and may not be the lot that you receive.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - STOT RE 2

Organi bersaglio

hearing organs

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

71.6 °F - closed cup

Punto d’infiammabilità (°C)

22.0 °C - closed cup


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Certificati d'analisi (COA)

Lot/Batch Number

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A validated GC?MS method for the determination and quantification of residual solvents in counterfeit tablets and capsules.
Deconinck E, et al.
Journal of Pharmaceutical and Biomedical Analysis, 70(1-2), 64-70 (2012)
Static headspace gas chromatographic method for quantitative determination of residual solvents in pharmaceutical drug substances according to European Pharmacopoeia requirements.
Otero R, et al.
Journal of Chromatography A, 1057(1-2), 193-201 (2004)
E Jindrová et al.
Folia microbiologica, 47(2), 83-93 (2002-06-13)
Several aerobic metabolic pathways for the degradation of benzene, toluene, ethylbenzene and xylene (BTEX), which are provided by two enzymic systems (dioxygenases and monooxygenases), have been identified. The monooxygenase attacks methyl or ethyl substituents of the aromatic ring, which are
Abby A Li et al.
Neurotoxicology, 31(3), 247-258 (2010-02-23)
The potential for neurotoxicological and immunotoxicological effects of ethylbenzene was studied in young adult Crl:CD(SD) rats following 90-day oral (neurotoxicity) or 28-day inhalation (immunotoxicity) exposures. In the neurotoxicity study, ethylbenzene was administered orally via gavage twice daily at 0, 25
W Tang et al.
Toxicology, 144(1-3), 39-50 (2000-04-27)
In the present studies, human exposure to styrene and to ethylbenzene (EB) is assessed on the basis of literature data. Total styrene and total EB exposure result from inhalation and from food intake. Styrene and EB inhaled represent the greatest

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