PHR1195
Tinidazole Related Compound A
Pharmaceutical Secondary Standard; Certified Reference Material
Sinonimo/i:
2-Methyl-4(5)-nitroimidazole, 2-METHYL-5-NITROIMIDAZOLE, Metronidazole Impurity A
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About This Item
Formula empirica (notazione di Hill):
C4H5N3O2
Numero CAS:
Peso molecolare:
127.10
Beilstein:
4032
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24
Prodotti consigliati
Grado
certified reference material
pharmaceutical secondary standard
Livello qualitativo
agenzia
traceable to Ph. Eur. Y0000087
traceable to USP 1667530
Famiglia di API
tinidazole
CdA
current certificate can be downloaded
tecniche
HPLC: suitable
gas chromatography (GC): suitable
Punto di fusione
251-255 °C (lit.)
applicazioni
pharmaceutical (small molecule)
Formato
neat
Temperatura di conservazione
2-8°C
Stringa SMILE
Cc1ncc([nH]1)[N+]([O-])=O
InChI
1S/C4H5N3O2/c1-3-5-2-4(6-3)7(8)9/h2H,1H3,(H,5,6)
FFYTTYVSDVWNMY-UHFFFAOYSA-N
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Descrizione generale
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Applicazioni
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Risultati analitici
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Altre note
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Nota a piè di pagina
To see an example of a Certificate of Analysis for this material enter LRAA9011 in the slot below. This is an example certificate only and may not be the lot that you receive.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Acute Tox. 4 Oral
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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Daniel D Rossouw et al.
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The inflammation- and infection-seeking properties of (131)I-labeled ornidazole, a 5-nitroimidazole derivative, have recently been reported. Whole-body images in rabbits showed a more rapid uptake in inflamed areas compared to (67)Ga. In the present study, two novel (123)I-labeled 2-methyl-4-nitroimidazole derivatives were
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Yao xue xue bao = Acta pharmaceutica Sinica, 38(4), 260-263 (2003-08-02)
To study the synthesis and antibacterial activity of pyridonecarboxylic acid derivatives containing 2-methyl-5-nitroimidazol. Pyridonecarboxylic acid derivatives containing 2-methyl-5-nitroimidazol were synthesized primarily from 2-methyl-5-nitroimidazol, norfloxacin, ciprofloxacin, enoxacin via nucleophilic substitution and esterification. The antibacterial activity of the nine target compounds were
V Arjunan et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 97, 176-188 (2012-07-06)
The FTIR and FT-Raman spectra of 1,2-dimethyl-5-nitroimidazole and 2-methyl-5-nitroimidazole have been recorded in the regions 4000-400 and 4000-100 cm(-1), respectively. The conformational analyses were performed and the energies of the different possible conformers were determined. The geometry of different conformers
Y Henry et al.
International journal of radiation biology and related studies in physics, chemistry, and medicine, 51(5), 797-809 (1987-05-01)
Three analogous 5-nitroimidazoles, having radiosensitizing and cytotoxic properties, have been studied by pulse-radiolysis in N2O-saturated aqueous formate solutions. Rates of formation of the radicals ImNO2-. are found to have little pH dependence. Decay of the radicals always follows second-order kinetics.
K Walczak et al.
Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 52(7), 935-941 (1998-07-14)
1,8-Diazabicyclo[5.4.0]undec-7-ene salts of 2-methyl-4(5)-nitroimidazole or benzotriazole were obtained in crystalline form. Michael-type addition of these salts to (4S,5R)-(E)-4,6-di-O-acetyl-5-hydroxy-2-hexenal gave, after acetylation of the product, an isomeric mixture of acetylated 3-(azol-1-yl)-2,3-dideoxy-D-arabino-hexopyranosides and 3-(azol-1-yl)-2,3-dideoxy-D-ribo-hexofuranosides. Reaction of these peracetylated adducts with trimethylsilylated thymine
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