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P6863

Sigma-Aldrich

PDAM

≥70% purity (HPLC), for HPLC derivatization, solid

Sinonimo/i:

1-Pyrenyldiazomethane, Pyrene, 1-(diazomethyl)

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About This Item

Formula empirica (notazione di Hill):
C17H10N2
Numero CAS:
Peso molecolare:
242.27
Numero MDL:
Codice UNSPSC:
12171500
ID PubChem:
NACRES:
MA.02

product name

PDAM, for HPLC derivatization

Grado

for HPLC derivatization

Livello qualitativo

Saggio

≥70% (HPLC)

Forma fisica

solid

λmax

338-344 nm

Fluorescenza

λem 371-379 nm

applicazioni

diagnostic assay manufacturing
hematology
histology

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

[N-]=[N+]=Cc1ccc2ccc3cccc4ccc1c2c34

InChI

1S/C17H10N2/c18-19-10-14-7-6-13-5-4-11-2-1-3-12-8-9-15(14)17(13)16(11)12/h1-10H
PEIBAWRLFPGPAT-UHFFFAOYSA-N

Applicazioni

Fluorescent diazoalkane useful as an HPLC derivatization reagent for carboxylic acid detection with better detection limit parameters and greater chemical stability than the commonly used 9-anthryldiazomethane.

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Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Liquid chromatographic determination of biotin by using 1-pyrenyldiazomethane as a pre-column fluorescent labelling reagent.
T Yoshida et al.
Journal of chromatography, 456(2), 421-426 (1988-12-16)
G A Mills et al.
Journal of chromatography. B, Biomedical sciences and applications, 730(1), 113-122 (1999-08-07)
Short chain fatty acids (SFCAs) are nutritionally important products of colonic bacteria. Their analysis in faeces is problematic. We report a headspace solid-phase microextraction procedure in which faecal SCFAs are derivatised on the fibre in-situ with 1-pyrenyldiazomethane. With this method
O L Brekke et al.
Journal of lipid research, 38(9), 1913-1922 (1997-11-05)
A highly sensitive method to determine agonist-induced release of endogenous fatty acids from cells in culture was developed using high-performance liquid chromatography and fluorescence detection. Fatty acids were selectively derivatized with 1-pyrenyldiazomethane and separated on a LC18 reversed phase column
Vladimir B Ritov et al.
Analytical biochemistry, 311(1), 10-18 (2002-11-21)
F(2)-isoprostanes are produced during free radical oxidation of cell phospholipids and are considered reliable biomarkers of oxidative stress. Currently, mass spectroscopy is the method of choice to detect F(2)-isoprostanes. However, due to numerous isomeric forms, analysis of F(2)-isoprostanes using MS
Junko Amano et al.
Analytical chemistry, 82(20), 8738-8743 (2010-09-25)
Glycoproteomics holds the promise of new advances in medical technology. However, mass spectrometry has limitations for the structural determination of glycosylated peptides because the hydrophilic nature of the oligosaccharide moiety in glycopeptides is disadvantageous for ionization, and glycopeptides ionize much

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