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Documenti

E0753

Supelco

4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one

analytical standard, for drug analysis

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About This Item

Formula empirica (notazione di Hill):
C12H11NO3
Numero CAS:
15646-46-5
Peso molecolare:
217.22
Numero CE:
239-713-9
Numero MDL:
MFCD00003204
Codice UNSPSC:
41116107
ID PubChem:
329798987
NACRES:
NA.24

Grado

analytical standard, for drug analysis

Livello qualitativo

200

Saggio

≥90% (HPLC)

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Punto di fusione

94-96 °C (dec.) (lit.)

applicazioni

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

CCO\C=C1/N=C(OC1=O)c2ccccc2

InChI

1S/C12H11NO3/c1-2-15-8-10-12(14)16-11(13-10)9-6-4-3-5-7-9/h3-8H,2H2,1H3/b10-8-
SJHPCNCNNSSLPL-NTMALXAHSA-N

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Categorie correlate

Applicazioni

4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one has been used as a haptenizing agent, which can induce an inflammatory reaction in adult zebrafish intestinal tissues and this can be used as a model for gene expression studies of the two forms of inflammatory bowel disease like Crohn′s disease and ulcerative colitis.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

Oxazolone sensitizing agent

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H317

Consigli di prudenza

P280

Classi di pericolo

Skin Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
0000325397
0000325400
0000325398
0000260547
0000260545

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Supelco

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Amalie W Arildsen et al.
Frontiers in immunology, 12, 650621-650621 (2021-04-06)
Epidemiological studies have long reported that perturbations of the childhood microbiome increase the risk of developing allergies, but a causal relationship with atopic dermatitis remains unclear. Here we colonized germ-free mice at birth or at one or eight week-of-age to
Ann Laigaard et al.
Scientific reports, 10(1), 21204-21204 (2020-12-05)
Atopic dermatitis is a chronic eczema commonly observed among children in Western countries. The gut microbiota is a significant factor in the pathogenesis, and ways to promote intestinal colonizers with anti-inflammatory capabilities are therefore favorable. The present study addressed the
Comparison of two chemically-induced colitis-models in adult zebrafish, using optical projection tomography and novel transcriptional markers
Haarder S, et al.
The Open Immunology Journal, 6, 154-154 (2016)
E J Putz et al.
PloS one, 14(10), e0223483-e0223483 (2019-10-10)
Hapten contact hypersensitivity (CHS) elicits a well-documented inflammation response that can be used to illustrate training of immune cells through hapten-specific CHS memory. The education of hapten-specific memory T cells has been well-established, recent research in mice has expanded the
Thomas Nolte et al.
Disease models & mechanisms, 6(1), 125-134 (2012-07-24)
Animal models mimicking human diseases have been used extensively to study the pathogenesis of autoimmune diseases and the efficacy of potential therapeutics. They are, however, limited with regard to their similarity to the human disease and cannot be used if
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