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D0740000

Dextromethorphan hydrobromide

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

Dextromethorphan hydrobromide monohydrate, (9S,13S,14S)-3-Methoxy-17-methylmorphinan hydrobromide

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100 MG
133,00 €

133,00 €

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100 MG
133,00 €

About This Item

Formula empirica (notazione di Hill):
C18H25NO · HBr · H2O
Numero CAS:
6700-34-1
Peso molecolare:
370.32
Beilstein:
6453793
Numero MDL:
MFCD02173901
Codice UNSPSC:
41116107
ID PubChem:
329798635
NACRES:
NA.24

133,00 €

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Grado

pharmaceutical primary standard

Famiglia di API

dextromethorphan

Produttore/marchio commerciale

EDQM

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

Br[H].[H]O[H].[H][C@]12CCCC[C@]13CCN(C)[C@H]2Cc4ccc(OC)cc34

InChI

1S/C18H25NO.BrH.H2O/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H;1H2/t15-,17+,18+;;/m1../s1
STTADZBLEUMJRG-IKNOHUQMSA-N

Informazioni sul gene

human ... GRIN2A(2903) , SIGMAR1(10280)

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Categorie correlate

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Dextromethorphan hydrobromide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Pittogrammi

Skull and crossbonesEnvironment
GHS06,GHS09

Avvertenze

Danger

Indicazioni di pericolo

H301,H411

Classi di pericolo

Acute Tox. 3 Oral - Aquatic Chronic 2

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number

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Supelco

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Sigma-Aldrich

D127

Dextrorphan tartrate

Dextrorphan

Sigma-Aldrich

UC205

Dextrorphan

Omeprazolo solid

Sigma-Aldrich

O104

Omeprazolo

Phenacetin ≥98.0% (HPLC)

Sigma-Aldrich

77440

Phenacetin

Diclofenac

Sigma-Aldrich

D6899

Diclofenac

F L Opdam et al.
Cancer chemotherapy and pharmacology, 71(3), 593-601 (2012-12-12)
Adjuvant therapy with tamoxifen significantly reduces breast cancer recurrence and mortality in estrogen receptor positive disease. CYP2D6 is the main enzyme involved in the activation of the prodrug tamoxifen into the anti-estrogen endoxifen. Endoxifen is thought to be a main
Fixed drug eruption due to dextromethorphan with tolerance to other opioids.
G Davila-Fernández et al.
Journal of investigational allergology & clinical immunology, 23(4), 281-282 (2013-08-24)
Melanie A Paquette et al.
The European journal of neuroscience, 36(9), 3224-3234 (2012-08-07)
Amantadine and dextromethorphan suppress levodopa (L-DOPA)-induced dyskinesia (LID) in patients with Parkinson's disease (PD) and abnormal involuntary movements (AIMs) in the unilateral 6-hydroxydopamine (6-OHDA) rat model. These effects have been attributed to N-methyl-d-aspartate (NMDA) antagonism. However, amantadine and dextromethorphan are
Tao-Cheng Wu et al.
PloS one, 7(9), e46067-e46067 (2012-10-11)
Vascular oxidative stress may be increased with age and aggravate endothelial dysfunction and vascular injury in hypertension. This study aimed to investigate the effects of dextromethorphan (DM), a NADPH oxidase inhibitor, either alone or in combination treatment, on blood pressure
Ewa Tomczak et al.
Archiwum medycyny sadowej i kryminologii, 62(3), 197-202 (2013-05-09)
The study highlighted the problem of intoxication using substances and/or preparations, to which nowadays young people have unrestricted access. Based on the case developed in the Department of Forensic Medicine of the Medical University of Gdansk, our team members were
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Protocolli

Thin Layer Chromatography Identification Test for Dextromethorphan following European Pharmacopeia Monograph on Silica Gel G 254 Plates

Silica gel G 254 plates are suitable for analysis of Dextromethorphan following the European pharmacopeia monograph.

Domande

Recensioni

Nessuna valutazione

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