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D0730000

Dexpanthenol

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

D-Panthenol, (R)-(+)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide, (R)-2,4-Dihydroxy-3,3-dimethylbutyric 3-hydroxypropylamide, D-Pantothenyl alcohol, Dexpanthenol, Provitamin B

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About This Item

Formula empirica (notazione di Hill):
C9H19NO4
Numero CAS:
Peso molecolare:
205.25
Beilstein:
1724947
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Origine biologica

synthetic

Grado

pharmaceutical primary standard

agenzia

EP Reference Standard

Famiglia di API

dexpanthenol

Forma fisica

solid

Produttore/marchio commerciale

EDQM

tecniche

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Densità

1.20 g/mL at 20 °C (lit.)

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

CC(C)(CO)[C@@H](O)C(=O)NCCCO

InChI

1S/C9H19NO4/c1-9(2,6-12)7(13)8(14)10-4-3-5-11/h7,11-13H,3-6H2,1-2H3,(H,10,14)/t7-/m0/s1
SNPLKNRPJHDVJA-ZETCQYMHSA-N

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Dexpanthenol, an alcoholic analog of pantothenic acid, can be potentially applied for skin wound healing application. It is utilized in multi-vitamin formulations, as a parenteral drug and certain cosmetic preparations. When absorbed by the skin, it is transformed into pantothenic acid (vitamin B5), which has implications in the biosynthesis of coenzyme A.

Applicazioni

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Prodotti correlati

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Anti-inflammatory and anti-oxidative effects of dexpanthenol on lipopolysaccharide induced acute lung injury in mice
Li-Mei W, et al.
Inflammation, 39(5), 1757-1763 (2016)
Simultaneous quantification of dexpanthenol and resorcinol from hair care formulation using liquid chromatography: method development and validation
De, Amit Kumar and Chowdhury, Partha Pratim and Chattapadhyay, Shyamaprasad
Scientifica, 2016(3), 983-988 (2016)
Dexpanthenol
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 2016(3), 2227-2228 (2017)
Simultaneous determination of mepyramine maleate, lidocaine hydrochloride, and dexpanthenol in pharmaceutical preparations by partial least-squares multivariate calibration
Aksu O, et al.
Analytical Letters, 39(4), 751-761 (2006)
Development and validation of reversed phase high performance liquid chromatography method for determination of dexpanthenol in pharmaceutical formulations.
Kulikov U A and Zinchenko A A.
Journal of Pharmaceutical and Biomedical Analysis, 43(3), 983-988 (2007)

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