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81210

Sigma-Aldrich

Poli(etilenglicole)

average Mw 1,500

Sinonimo/i:

PEG

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About This Item

Formula condensata:
H(OCH2CH2)nOH
Numero CAS:
25322-68-3
Numero MDL:
MFCD00081839
Codice UNSPSC:
12352104
ID PubChem:
24887690
NACRES:
NA.23

product name

Poli(etilenglicole), average Mw 1,500

Forma fisica

solid

Livello qualitativo

200

PM

average Mw 1,500

Punto di fusione

45-50 °C

Temp. transizione

Tm 45-50 °C

Estremità Ω

hydroxyl

Estremità α

hydroxyl

Stringa SMILE

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, required for the purification of biological materials. PEG also interacts with cell membrane, thereby resulting in cell fusion.

Applicazioni

Poly(ethylene glycol) has been used for histological, histochemical and immunohistochemical evaluation of in vitro cultured beads. It has been used for the fusion of cells.

Altre note

Molecular weight range: 1,400-1,600

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
BCCK3982
BCCH2553
BCCH2552
BCCD3122
BCCB0461

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Poli(etilenglicole) average mol wt 400

Sigma-Aldrich

P3265

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Sigma-Aldrich

295906

Poli(etilenglicole)

Chondrogenesis of human mesenchymal stem cells encapsulated in alginate beads.
Ma HL et al.
Journal of Biomedical Materials Research Part A, 64, 273-273 (2003)
DC-SIGN (CD209) expression is IL-4 dependent and is negatively regulated by IFN, TGF-beta, and anti-inflammatory agents.
Relloso M et al.
Journal of Immunology, 168, 2634-2634 (2002)
Poly (ethylene glycol) in drug delivery: pros and cons as well as potential alternatives.
Angewandte Chemie (International Edition in English), 49, 6288-6308 (2010)
Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications (2013)
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
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Articoli

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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