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Merck
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Documenti fondamentali

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69369

Supelco

3-Methylmalic acid

≥95.0% (HPLC)

Sinonimo/i:

β-Methylmalic acid, (±)-2-Hydroxy-3-methylbutandioic acid, 2-Hydroxy-3-methylsuccinic acid

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About This Item

Formula empirica (notazione di Hill):
C5H8O5
Numero CAS:
608-41-3
Peso molecolare:
148.11
Beilstein:
1773280
Numero MDL:
MFCD19228449
Codice UNSPSC:
41116107
ID PubChem:
329761612
NACRES:
NA.24

Livello qualitativo

100

Saggio

≥95.0% (HPLC)

applicazioni

clinical testing

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

OC(C(C)C(O)C(O)=O)=O

InChI

1S/C5H8O5/c1-2(4(7)8)3(6)5(9)10/h2-3,6H,1H3,(H,7,8)(H,9,10)
NPYQJIHHTGFBLN-UHFFFAOYSA-N

Azioni biochim/fisiol

Metabolite of C5-branched dibasic acid metabolism, valine, leucine and isoleucine biosynthesis and 2-oxocarboxylic acid metabolism.

Pittogrammi

Corrosion
GHS05

Avvertenze

Danger

Indicazioni di pericolo

H318

Classi di pericolo

Eye Dam. 1

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
BCBP9394V
BCBP9394

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D T Loots
Journal of inherited metabolic disease, 32(3), 403-411 (2009-04-04)
Although a number of abnormal diagnostic metabolites have previously been described in the urine of patients with isovaleric acidaemia (IVA), they do not fully explain the clinical symptoms associated with this disease. On the basis of our current understanding of
I Roymoulik et al.
Biochemistry, 39(33), 10340-10346 (2000-08-24)
Adenosylcobalamin-dependent enzymes catalyze a variety of chemically difficult isomerizations in which a nonacidic hydrogen on one carbon is interchanged with an electron-withdrawing group on an adjacent carbon. We describe a new isomerization, that of L-2-hydroxyglutarate to L-threo-3-methylmalate, involving the migration
Sylvia Herter et al.
The Journal of biological chemistry, 277(23), 20277-20283 (2002-04-04)
Phototrophic CO(2) assimilation by the primitive, green eubacterium Chloroflexus aurantiacus has been shown earlier to proceed in a cyclic mode via 3-hydroxypropionate, propionyl-CoA, succinyl-CoA, and malyl-CoA. The metabolic cycle could be closed by cleavage of malyl-CoA affording glyoxylate (the primary
Juliane Elisa Welke et al.
Journal of chromatography. A, 1226, 124-139 (2012-01-27)
Wine aroma is an important characteristic and may be related to certain specific parameters, such as raw material and production process. The complexity of Merlot wine aroma was considered suitable for comprehensive two-dimensional gas chromatography (GC×GC), as this technique offers
Laura Strittmatter et al.
Human molecular genetics, 23(9), 2313-2323 (2013-12-18)
CLYBL is a human mitochondrial enzyme of unknown function that is found in multiple eukaryotic taxa and conserved to bacteria. The protein is expressed in the mitochondria of all mammalian organs, with highest expression in brown fat and kidney. Approximately
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