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Supelco

Silychristin

analytical standard

Sinonimo/i:

Silymarin II

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About This Item

Formula empirica (notazione di Hill):
C25H22O10
Numero CAS:
Peso molecolare:
482.44
Numero CE:
Numero MDL:
Codice UNSPSC:
85151701
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Saggio

≥90.0% (HPLC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Impurezze

≤10.0% water

applicazioni

food and beverages

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

COc1cc(ccc1O)[C@@H]2Oc3c(O)cc(cc3[C@H]2CO)[C@H]4Oc5cc(O)cc(O)c5C(=O)[C@@H]4O

InChI

1S/C25H22O10/c1-33-18-6-10(2-3-15(18)28)23-14(9-26)13-4-11(5-17(30)25(13)35-23)24-22(32)21(31)20-16(29)7-12(27)8-19(20)34-24/h2-8,14,22-24,26-30,32H,9H2,1H3/t14-,22+,23+,24-/m1/s1
BMLIIPOXVWESJG-LMBCONBSSA-N

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Descrizione generale

Silychristin is one of the congeners of flavonolignan silybin. It is usually derived from silymarin, which is extracted from the fruits of Silybum marianum (L.) Gaertn, and Asteraceae (Carduus marianus L.; milk thistle).

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Silychristin may be used as an analytical reference standard for the determination of silychristin in:
  • Herbal extracts, fruit extracts, and seed extracts of Silybum marianum by ultra-high performance liquid chromatography with diode array detection (UHPLC-DAD) and methanol extraction coupled to HPLC equipped with ultraviolet array detection (UVAD).
  • Milk thistle seeds by HPLC-UV.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

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Jose F Barreto et al.
Applied biochemistry and biotechnology, 105 -108, 881-889 (2003-05-02)
Milk thistle contains compounds that display hepatoxic protection properties. We examined the batch extraction of silymarin compounds from milk thistle seed meal in 50, 70, 85, and 100 degrees C water as a function of time. After 210 min of
Wendy A Smith et al.
Planta medica, 71(9), 877-880 (2005-10-06)
A new natural product has been isolated from silymarin, the hepatoprotective extract of milk thistle (Silybum marianum) fruits. This was shown by NMR spectroscopy to be silychristin B (8), a diastereoisomer of the known silychristin (7). Levels of these and
Pharmacokinetics of pure silybin diastereoisomers and identification of their metabolites in rat plasma.
Marhol P, et al.
Journal of functional foods, 14, 570-580 (2015)
Optimization and single-laboratory validation of a method for the determination of flavonolignans in milk thistle seeds by high-performance liquid chromatography with ultraviolet detection.
Mudge E, et al.
Analytical and Bioanalytical Chemistry, 407(25), 7657-7666 (2015)
J Sonnenbichler et al.
The Journal of pharmacology and experimental therapeutics, 290(3), 1375-1383 (1999-08-24)
The biochemical influence of flavonolignans from the milk thistle Silybum marianum has been tested on kidney cells of African green monkeys. Two nonmalignant cell lines were selected, with the focus of the work on the fibroblast-like Vero line. Proliferation rate

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