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484407

Sigma-Aldrich

1-Methoxy-2-propanol

greener alternative

≥99.5%

Sinonimo/i:

Propylene glycol methyl ether, Propyleneglycol monomethyl ether

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About This Item

Formula condensata:
CH3CH(OH)CH2OCH3
Numero CAS:
107-98-2
Peso molecolare:
90.12
Beilstein:
1731270
Numero CE:
203-539-1
Numero MDL:
MFCD00004537
Codice UNSPSC:
12352100
ID PubChem:
57651153
NACRES:
NA.21

Densità del vapore

3.12 (vs air)

Livello qualitativo

200

Tensione di vapore

10.9 mmHg ( 25 °C)

Nome Commerciale

ReagentPlus®

Saggio

≥99.5%

Forma fisica

liquid

Temp. autoaccensione

532 °F

Limite di esplosione

13.8 %

Caratteristiche più verdi

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Impurezze

≤0.001% water

Indice di rifrazione

n20/D 1.403 (lit.)

P. eboll.

118-119 °C (lit.)

Punto di fusione

-97 °C

Solubilità

water: miscible

Densità

0.916 g/mL at 25 °C (lit.)

applicazioni

microbiology

Categoria alternativa più verde

, Aligned

Stringa SMILE

CC(O)COC

InChI

1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3
ARXJGSRGQADJSQ-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

1-Methoxy-2-propanol (Propylene glycol methyl ether, PGME), a glycol ether, can be synthesized by reacting propylene oxide with methanol in the presence of ZnMgAl (zinc-magnesium-aluminium) catalysts. Its degradation by microorganisms in different soil types has been investigated. An oral reference dose (RfD) and an inhalation reference concentration (RfC) values of PGME have been obtained from inhalation studies in F344 rats and B6C3F1 mice.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry.Monoethers, especially propylene glycol methyl ether (PGME), are widely used as pollution-free solvents in fine chemical synthesis in pharmaceutical, chemical and cosmetic industries and thus aligns with "Safer Solvents and Auxiliaries". Click here for more information.

Note legali

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pittogrammi

FlameExclamation mark
GHS02,GHS07

Avvertenze

Warning

Indicazioni di pericolo

H226,H336

Classi di pericolo

Flam. Liq. 3 - STOT SE 3

Organi bersaglio

Central nervous system

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

93.2 °F - closed cup

Punto d’infiammabilità (°C)

34 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificati d'analisi (COA)

Lot/Batch Number
STBL4198
MKCW2242
MKCW0598
MKCW1794
SDBB1290

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3-Ethoxy-1-propanol 97%

Sigma-Aldrich

E7401

3-Ethoxy-1-propanol

Propylene glycol propyl ether 99%

Sigma-Aldrich

424927

Propylene glycol propyl ether

Influence of acid-base properties of ZnMgAl-mixed oxides for the synthesis of 1-methoxy-2-propanol.
Cheng W, et al.
Applied Clay Science, 42(1), 111-115 (2008)
Biodegradation of glycol ethers in soil.
Gonsior SJ and West RJ.
Environmental Toxicology and Chemistry / Setac, 14(8), 1273-1279 (1995)
Rei Momose et al.
Organic letters, 15(8), 2010-2013 (2013-04-11)
Three new alkaloids, hyrtimomines A-C (1-3), were isolated from an Okinawan marine sponge Hyrtios sp. The structures of 1-3 were elucidated on the basis of spectroscopic analysis and application of a phenylglycine methyl ester (PGME) method. Hyrtimomines A (1) and
C R Kirman et al.
Risk analysis : an official publication of the Society for Risk Analysis, 25(2), 271-284 (2005-05-07)
Reference values, including an oral reference dose (RfD) and an inhalation reference concentration (RfC), were derived for propylene glycol methyl ether (PGME), and an oral RfD was derived for its acetate (PGMEA). These values were based on transient sedation observed
Juergen Brieger et al.
Toxicology letters, 177(2), 138-143 (2008-02-26)
To evaluate the impact of 1-methoxypropanol-2 (MEP) for the stimulation of an inflammatory response in human respiratory mucosa, we exposed 22 primary cell cultures of nasal respiratory epithelia of healthy individuals to MEP concentrations at the level of the German
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