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Supelco

Triclabendazole sulfoxide

VETRANAL®, analytical standard

Sinonimo/i:

5-Chloro-6-(2,3-dichlorophenoxy)-2-(methylsulfinyl)-1H-benzimidazole

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10 MG
148,00 €

148,00 €

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10 MG
148,00 €

About This Item

Formula empirica (notazione di Hill):
C14H9Cl3N2O2S
Numero CAS:
100648-13-3
Peso molecolare:
375.66
Beilstein:
5829656
Numero MDL:
MFCD09038493
Codice UNSPSC:
41116107
ID PubChem:
329755152
NACRES:
NA.24

148,00 €

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Richiedi un ordine bulk

Grado

analytical standard

Livello qualitativo

100

Nome Commerciale

VETRANAL®

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

forensics and toxicology
pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

CS(=O)c1nc2cc(Cl)c(Oc3cccc(Cl)c3Cl)cc2[nH]1

InChI

1S/C14H9Cl3N2O2S/c1-22(20)14-18-9-5-8(16)12(6-10(9)19-14)21-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)
GABQPFWIQFRJSE-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

Triclabendazole sulfoxide belongs to the benzimidazole class of anthelmintics drugs.[1][2] It is very much effective against mature and immature stages of Fasciola hepatica and Fasciola gigantica in all ruminant species.[2]

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Note legali

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

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Certificati d'analisi (COA)

Lot/Batch Number
BCCL1071
BCCG3902
BCCD1858
BCCB5255
BCBW3825

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F Imperiale et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 28(4), 438-445 (2011-02-22)
Triclabendazole (TCBZ) is a flukicidal halogenated benzimidazole compound extensively used in veterinary medicine. Liver fluke control in lactating dairy cattle is difficult because treatment should be implemented only during the dry period to avoid milk residues. However, control in endemic
Mark W Robinson et al.
Parasitology research, 92(3), 205-210 (2003-12-04)
Benzimidazole anthelmintics are widely used against nematode, cestode and trematode parasites. The drugs undergo several enzyme-mediated reactions within the host animal that produce a number of metabolites. Although it has been shown that certain helminths, including Fasciola hepatica, can metabolise
G Virkel et al.
Journal of veterinary pharmacology and therapeutics, 29(3), 213-223 (2006-05-04)
Triclabendazole (TCBZ) is an halogenated benzimidazole (BZD) compound worldwide used to control immature and adult stages of the liver fluke Fasciola hepatica. The purpose of this investigation was to characterize in vitro the patterns of hepatic and ruminal biotransformation of
M Meaney et al.
Parasitology research, 88(4), 315-325 (2002-05-10)
The effect of the active sulphoxide metabolite of the fasciolicide triclabendazole on the surface morphology of the tropical liver fluke, Fasciola gigantica, was determined in vitro by scanning electron microscopy. At a concentration of 10 microg/ml, swelling and blebbing of
L Halferty et al.
Veterinary parasitology, 159(2), 126-138 (2008-11-26)
A study has been carried out to determine the relative activity of triclabendazole (TCBZ) and its sulphoxide (TCBZSO) and sulphone (TCBZSO(2)) metabolites against the adult stage of the liver fluke, Fasciola hepatica. Flukes were incubated for 24h in vitro in
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