Pirbuterol acetate

Name: Pirbuterol acetate
Brand: SIAL

VETRANAL^®, analytical standard

Sinonimo/i:

(RS)-2-(tert-Butylamino)-1-(6-hydroxymethyl-5-hydroxy-2-pyridyl)ethanol acetate salt, 6-(2-tert-Butylamino-1-hydroxyethyl)-2-hydroxymethylpyridin-3-ol acetate

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Informazioni su questo articolo

Formula empirica (notazione di Hill):

C₁₂H₂₀N₂O₃ · C₂H₄O₂

Numero CAS:

65652-44-0

Peso molecolare:

300.35

PubChem Substance ID:

329754063

UNSPSC Code:

41116107

NACRES:

NA.24

EC Number:

265-862-4

MDL number:

MFCD07773091

Beilstein/REAXYS Number:

13318829

Documenti fondamentali

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grade

analytical standard

Quality Level

100

product line

VETRANAL^®

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

N(C(C)(C)C)CC(O)c1nc(c(cc1)O)CO.OC(=O)C

InChI

1S/C12H20N2O3.C2H4O2/c1-12(2,3)13-6-11(17)8-4-5-10(16)9(7-15)14-8;1-2(3)4/h4-5,11,13,15-17H,6-7H2,1-3H3;1H3,(H,3,4)

InChI key

QSXMZJGGEWYVCN-UHFFFAOYSA-N

Gene Information

human ... ADRB2(154)

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Categorie correlate

Analytical Chromatography

Chromatography Standards

Reference Materials

Analytical Chemistry

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Questo articolo	PHR1752	PHR3640	32143
Supelco 32142 Pirbuterol acetate	Supelco PHR1752 Bupropion Hydrochloride Related Compound A	Supelco PHR3640 4-[(1RS)-2-(tert-Butylamino)-1-hydroxyethyl]-2-ethylphenol hydrochloride	Supelco 32143 Salbutamol-(tert-butyl-d₉) acetate
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) -	technique(s) HPLC: suitable, gas chromatography (GC): suitable
grade analytical standard	grade certified reference material, pharmaceutical secondary standard	grade certified reference material, pharmaceutical secondary standard	grade analytical standard
application(s) forensics and toxicology pharmaceutical (small molecule) veterinary	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical	application(s) forensics and toxicology veterinary
format neat	format neat	format -	format neat
product line VETRANAL^®	product line -	product line -	product line VETRANAL^®
Quality Level 100	Quality Level 300	Quality Level 300	Quality Level 100

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

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Double-blind, clinical efficacy study comparing 400 micrograms of pirbuterol versus placebo delivered by a breath-actuated aerosol inhaler.

D G Tinkelman et al.

The Journal of asthma : official journal of the Association for the Care of Asthma, 31(3), 187-192 (1994-01-01)

Pirbuterol is a selective beta-2 adrenergic agonist that is indicated for the treatment of bronchospasm in patients with asthma. Traditionally, the most common form of administration of the beta-2 agonist is by inhalation from a pressurized metered-dose inhaler. The purpose

A device for overcoming discoordination with metered-dose inhalers.

M H Schecker et al.

The Journal of allergy and clinical immunology, 92(6), 783-789 (1993-12-01)

Despite widespread acceptance of metered-dose inhalers (MDIs) in the treatment of asthma, many patients fail to operate these devices correctly. Inability to properly coordinate activation with onset of inhalation is regarded as the major factor in suboptimal MDI therapy. We

Aerosol pirbuterol: bronchodilator activity and side effects in ponies with recurrent airway obstruction (heaves).

F J Derksen et al.

Equine veterinary journal, 24(2), 107-112 (1992-03-01)

The dose of aerosol pirbuterol that could be administered safely to ponies (weight approximately 200 kg) was determined by observation for sweating, trembling and excitement and measurement of heart and respiratory rates during cumulative administration of the drug. Sweating, trembling

The utility of the forced oscillation technique in assessing bronchodilator responsiveness in patients with asthma.

Makito Yaegashi et al.

Respiratory medicine, 101(5), 995-1000 (2006-10-24)

To address the utility of the forced oscillation technique (FOT) in assessing bronchodilator responsiveness compared with forced expiratory volume in 1s (FEV(1)). This is a retrospective analysis of consecutive 126 patients with a clinical history of asthma without any other

Salbutamol, terbutaline and pirbuterol allergy in an asthmatic patient.

P Bonniaud et al.

Allergy, 62(10), 1219-1220 (2007-09-12)

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Numero articolo commerciale globale

SKU	GTIN
32142-10MG	04061826702291

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Pirbuterol acetate