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Key Documents

31493

Sigma-Aldrich

Sodium salicylate

puriss. p.a., reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance)

Sinonimo/i:

2-Hydroxybenzoic acid sodium salt, Salicylic acid sodium salt, Sodium 2-hydroxybenzoate

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About This Item

Formula condensata:
HOC6H4COONa
Numero CAS:
Peso molecolare:
160.10
Beilstein:
3732792
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.21

agenzia

USP/NF
reag. Ph. Eur.

Livello qualitativo

Grado

puriss. p.a.

Saggio

99.5-101.0% (calc. to the dried substance)

Impurezze

acidic reac. impurities, complies
sulfite or thiosulfate, complies
≤0.001% heavy metals (as Pb)

Perdita

≤0.3% loss on drying, 105 °C

Punto di fusione

>300 °C (lit.)

Anioni in tracce

chloride (Cl-): ≤20 mg/kg
sulfate (SO42-): ≤500 mg/kg

Cationi in tracce

Fe: ≤10 mg/kg

Compatibilità

in accordance for appearance of solution

Stringa SMILE

[Na+].Oc1ccccc1C([O-])=O

InChI

1S/C7H6O3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1
ABBQHOQBGMUPJH-UHFFFAOYSA-M

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Descrizione generale

Sodium salicylate can be prepared from the reaction of salicylic acid and ammonia. It exhibits fluorescence at higher concentrations and effectively absorbs β-particles. Due to these properties, it has been employed as fluor for the radioactivity detection in various gels.

Applicazioni

Sodium salicylate may be used as phenolic reagent in salicylate method for the determination of ammonia. It may be employed as a hydrotropic agent to study the release of anticancer drug camptothecin (CPT) from the mixed micelles [composed of Pluronic P105 (P105) and D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS)].

Pittogrammi

Health hazardExclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

208.9 °F - Pensky-Martens closed cup

Punto d’infiammabilità (°C)

98.3 °C - Pensky-Martens closed cup

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Yan Gao et al.
Colloids and surfaces. B, Biointerfaces, 64(2), 194-199 (2008-03-08)
To increase the solubility and cytotoxicity of poorly soluble anticancer drug camptothecin (CPT), mixed micelles made of Pluronic P105 (P105) and d-alpha-tocopheryl polyethylene glycol 1,000 succinate (TPGS) were prepared. The interaction of Pluronic and TPGS was studied and critical micelle
Ammonia determination based on indophenol formation with sodium salicylate.
Verdouw H, et al.
Water Research, 12(6), 399-402 (1978)
Fluorographic detection of radioactivity in polyacrylamide gels with the water-soluble fluor, sodium salicylate.
J P Chamberlain
Analytical biochemistry, 98(1), 132-135 (1979-09-15)
Kui Wang et al.
Journal of medicinal chemistry, 52(20), 6402-6412 (2009-10-16)
Viologens are showing an increasing number of scientific and technical applications in addition to their use as herbicides. However, their high toxicity poses considerable risks to human health, society, and the environment. In this context, we propose a new therapeutic
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Animal models of tinnitus require a behavioral correlate thereof. Various conditioned response methods and gap-startle reflex methods are in use and the outcomes generally correspond with putative electrophysiological substrates of tinnitus. However, for salicylate-induced tinnitus there is discordance between the

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