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229253

Sigma-Aldrich

Carminic acid

≥90% (HPLC)

Sinonimo/i:

Natural Red 4

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About This Item

Formula empirica (notazione di Hill):
C22H20O13
Numero CAS:
Peso molecolare:
492.39
Colour Index:
75470
Beilstein:
71651
Numero CE:
Numero MDL:
Codice UNSPSC:
12171500
ID PubChem:
NACRES:
NA.47

Livello qualitativo

Saggio

≥90% (HPLC)

Forma fisica

powder

Attività ottica

[α]20/D +3.1°, c = 1 in H2O

Colore

purple to red-purple
red to very dark red

Punto di fusione

136 °C

Solubilità

1 N acetic acid: 1%, clear to hazy, red

λmax

495 nm

ε (coefficiente d’estinzione)

≥13000 at 222-228  nm in ethanol at 0.03 g/L
≥18000 at 275-281 nm in ethanol at 0.03 g/L

applicazioni

diagnostic assay manufacturing
hematology
histology

Temperatura di conservazione

room temp

Stringa SMILE

Cc1c(C(O)=O)c(O)cc2C(=O)c3c(O)c(O)c([C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(O)c3C(=O)c12

InChI

1S/C22H20O13/c1-4-8-5(2-6(24)9(4)22(33)34)13(25)10-11(15(8)27)16(28)12(18(30)17(10)29)21-20(32)19(31)14(26)7(3-23)35-21/h2,7,14,19-21,23-24,26,28-32H,3H2,1H3,(H,33,34)/t7-,14-,19+,20-,21+/m1/s1
DGQLVPJVXFOQEV-JNVSTXMASA-N

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Categorie correlate

Descrizione generale

Carmine is a cochineal product usually furnished as an aluminum and calcium salt of carminic acid. Carminic acid is used for human-medical cell diagnosis and serves the purpose of the histological investigation of sample material of human origin. It is suitable for staining nuclei in histological sections. It is utilized in various staining methods including the procedure for detection of glycogen and mucous substances (Best′s carmine), for nuclear staining, or vital staining.

Applicazioni

Carminic acid (CI 75470) is used in Orth′s lithium carmine technique for nuclear staining, Best′s stain for glycogen, and Southgates′s mucicarmine method.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Gabriel J. Lauro, Jack Francis
Natural Food Colorants: Science and Technology (2000)
J.D. Houghton, G.A.F. Hendry
Natural Food Colorants (2012)
Ana Serrano et al.
Analytical and bioanalytical chemistry, 401(2), 735-743 (2011-06-01)
A new analytical approach based on high-performance liquid chromatography with diode array detector (HPLC-DAD) and multivariate data analysis was applied and assessed for analyzing the red dye extracted from cochineal insects, used in precious historical textiles. The most widely used
Samanan Poowakanjana et al.
Journal of food science, 74(9), C707-C712 (2010-05-25)
Carmine used to color surimi seafood often seeps or bleeds from red-colored meat to white meat when vacuum-packed products go through high-temperature long-time pasteurization. Various physical and chemical treatments were examined to investigate means to inhibit or minimize carmine bleeding
Hajime Nakatani et al.
Bioscience, biotechnology, and biochemistry, 75(3), 550-555 (2011-03-11)
The interaction between mammary epithelial and stromal tissue is considered to be important in breast tissue development. In this study, we developed a transplantation procedure for the mammary stromal fibroblastic cell line (MSF) to examine its life in vivo. First

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