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06279

Supelco

Mangiferin

analytical standard

Sinonimo/i:

1,3,6,7-Tetrahydroxyxanthone C2-β-D-glucoside, Chinomin, Chinonin, Shamimin

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About This Item

Formula empirica (notazione di Hill):
C19H18O11
Numero CAS:
4773-96-0
Peso molecolare:
422.34
Numero MDL:
MFCD00075656
Codice UNSPSC:
85151701
ID PubChem:
329748228
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

100

Saggio

≥98.0% (TLC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

food and beverages

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc3Oc4cc(O)c(O)cc4C(=O)c3c2O

InChI

1S/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19+/m1/s1
AEDDIBAIWPIIBD-ZJKJAXBQSA-N

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Descrizione generale

Mangiferin is a xanthone glucoside and a naturally occurring polyphenol found abundantly in the plants of genus Mangifera particularly Mangifera indica L. and also in some medicinal herbs. Mangiferin exhibits antioxidant, antiviral, antitumor, anti-inflammatory and gene-regulatory effects and is considered to be of high research interest due to its therapeutic properties.

Applicazioni

Mangiferin may be used as an analytical standard for the determination of the analyte in rat plasma, traditional Chinese medicines and honeybush tea (Cyclopia spp.) by chromatography based techniques.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Altre note

This compound is commonly found in plants of the genus: hypericum

Pittogrammi

Skull and crossbones
GHS06

Avvertenze

Danger

Indicazioni di pericolo

H300

Classi di pericolo

Acute Tox. 1 Oral

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Choose from one of the most recent versions:

Certificati d'analisi (COA)

Lot/Batch Number
BCCM3128
BCCJ6806
BCCG0797
BCCF0341
BCCB4323

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Dandan Han et al.
Journal of pharmaceutical and biomedical analysis, 51(1), 260-263 (2009-08-25)
An ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method employing electrospray ionization (ESI) has been developed for the determination of mangiferin in rat plasma using diphenhydramine as the internal standard (IS). Liquid-liquid extraction (LLE) was used for sample preparation and
High-performance liquid chromatographic method for the determination of mangiferin, likviritin and dihydroquercetin in rat plasma and urine
Geodakyan SV, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 577(2), 371-375 (1992)
Ronghua Dai et al.
Journal of chromatographic science, 42(4), 207-210 (2004-05-25)
High-performance liquid chromatography is employed to determine the contents of six marker components such as mangiferin, jateorrhizine, palmatine, berberine, cinnamic acid, and cinnamaldehyde in the traditional Chinese medicinal preparation Zi-Shen pill. The separation is performed on a C(18) column by
Reversed-phase HPLC determination of mangiferin, isomangiferin and hesperidin in Cyclopia and the effect of harvesting date on the phenolic composition of C. genistoides
Joubert E, et al.
European Food Research and Technology, 216(3), 270-273 (2003)
Hongzhong Li et al.
Toxicology and applied pharmacology, 272(1), 180-190 (2013-05-28)
Although mangiferin which is a naturally occurring glucosylxanthone has exhibited promising anticancer activities, the detailed molecular mechanism of mangiferin on cancers still remains enigmatic. In this study, the anticancer activity of mangiferin was evaluated in breast cancer cell line-based in
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