0017-FP

6`-suSiaLex-C3-PAA-fluo

• Codice UNSPSC: 12352201
• NACRES: NA.25

Proprietà

• carrier: PAA carrier
• label: FITC labeled
• Nome Commerciale: FP-Series
• Saggio: 95% (H-NMR)
• Forma fisica: lyophilized powder
• PM: ~20,000 Da
• Produttore/marchio commerciale: GlycoNZ
• Grado di funzionalizzazione: 1% Biotin per 20 mole % Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide] ligand density
• tecniche: flow cytometry: suitable
• probe type: tetrasaccharide
• probe presentation: polymeric
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

FP-Series: Fluorescein-Labeled Polymeric Probes
These glycoconjugate probes are designed to reveal lectins, including selectins, directly on cell membranes, organelles, and in cytoplasm. The low fluorescein content ensures that probe solubility in water is not affected, but still allows reliable probe detection. The affinity of the probes is 10² to 10⁵ times higher than that of corresponding free sugars.

PAA is poly[N-(2-hydroxyethyl)acrylamide], a flexible polymer chain which serves as an additional spacer. Used as a molecular weight carrier, PAA demonstrates an absence of non-specific interaction with cells, and is stable to chemical and proteolytic action.

Applicazioni

Glycoconjugates are used to study the functions of carbohydrates, carbohydrate-binding proteins in biological processes, and on the discovery of new carbohydrate-mediated interactions.

Nota sulla preparazione

Purity: synthetic ω-aminoalkyl glycosides used for coupling with the polymer have a purity of >95% (HPLC and ¹H-NMR)

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable