MABN79
Anti-BDNF Antibody, clone 8G8.2
clone 8G8.2, from mouse
Sinonimo/i:
BDNF, Brain-derived neurotrophic factor, Abrineurin
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About This Item
Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Prodotti consigliati
Origine biologica
mouse
Livello qualitativo
Forma dell’anticorpo
purified immunoglobulin
Tipo di anticorpo
primary antibodies
Clone
8G8.2, monoclonal
Reattività contro le specie
mouse
tecniche
western blot: suitable
Isotipo
IgG1κ
N° accesso NCBI
N° accesso UniProt
Condizioni di spedizione
wet ice
modifica post-traduzionali bersaglio
unmodified
Informazioni sul gene
human ... BDNF(627)
Descrizione generale
BDNF is a important neurotrophic factor essential for proper neuronal development and survival of various neuronal populations in the CNS and PNS. BDNF is also key for axonal growth and path finding of dendritic growth and morphology. BDNF also is key to neuronal responses and LTP or LTD and synaptic plasticity, behavior, learning and memory. BDNF is also important in neuronal disease and is being studied as potential marker in various diseases. Finally, BDNF is expressed initially as a proform protein long thought to simply be an inactive proform factor, however recent research demonstrates that proBDNF may play roles not only in neuronal development but also development in general as well as in adult metabolism in brain, muscle, and general metabolic function, so the research into BDNF is growing. BDNF is expressed developmentally in the brain and developing nervous system but it is also expressed in the adult in the brain, gut, muscle, lung, testis, prostate and placenta.
Immunogeno
KLH-conjugated linear peptide corresponding to human BDNF.
Applicazioni
Anti-BDNF Antibody, clone 8G8.2 is an antibody against BDNF for use in Western Blotting.
Qualità
Evaluated by Western Blotting in mouse brain membrane tissue lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected BDNF in 10 µg of mouse brain membrane tissue lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected BDNF in 10 µg of mouse brain membrane tissue lysate.
Descrizione del bersaglio
~25 kDa observed. UnitProt describes 5 isoforms produced by alternative promoter usage and alternative splicing ranging from 27.8 to 37.1 kDa
Stato fisico
Format: Purified
Altre note
Concentration: Please refer to lot specific datasheet.
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Raccomandato
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
12 - Non Combustible Liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
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