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MAB3402B

Sigma-Aldrich

Anti-GFAP Antibody, Biotin Conjugate | MAB3402B

from mouse, biotin conjugate

Sinonimo/i:

Glial fibrillary acidic protein, GFAP

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

Coniugato

biotin conjugate

Forma dell’anticorpo

purified antibody

Tipo di anticorpo

primary antibodies

Clone

monoclonal

Reattività contro le specie

pig, mouse

Reattività contro le specie (prevista in base all’omologia)

porcine (based on 100% sequence homology), human (based on 100% sequence homology), chicken (based on 100% sequence homology), rat (based on 100% sequence homology)

tecniche

immunohistochemistry: suitable

Isotipo

IgG1

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... GFAP(2670)

Descrizione generale

Glial fibrillary acidic protein is a class-III intermediate filament. GFAP is the main constituent of intermediate filaments in astrocytes and serves as a cell specific marker that distinguishes differentiated astrocytes from other glial cells during the development of the central nervous system.

Immunogeno

Purified glial filament protein (Debus, E., et al. (1983) Differentiation. 25:193-203.)

Applicazioni

Anti-GFAP Antibody, Biotin Conjugate detects level of GFAP & has been published & validated for use in IH.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience

Qualità

Evaluated by Immunohistochemistry in mouse adult brain tissue.

Immunohistochemistry Analysis: 1:100 dilution of this antibody detected GFAP in mouse adult brain tissue.

Descrizione del bersaglio

50 kDa calculated

Stato fisico

Protein A purified
Purified mouse monoclonal IgG1 conjugated to Biotin in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Stoccaggio e stabilità

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Risultati analitici

Control
Mouse adult brain tissue

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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One of the key pathological hallmarks of Alzheimer disease (AD) is the accumulation of the amyloid-β (Aβ) peptide into amyloid plaques. The apolipoprotein E (APOE) gene is the strongest genetic risk factor for late-onset AD and has been shown to
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Science translational medicine, 13(581) (2021-02-19)
The ε4 allele of the apolipoprotein E (APOE) gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD) and greatly influences the development of amyloid-β (Aβ) pathology. Our current study investigated the potential therapeutic effects of the anti-human
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The apolipoprotein E (APOE) gene is the strongest genetic risk factor for Alzheimer's disease and directly influences tauopathy and tau-mediated neurodegeneration. ApoE4 has strong deleterious effects on both parameters. In the brain, apoE is produced and secreted primarily by astrocytes
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Science advances, 9(16), eade1282-eade1282 (2023-04-19)
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