ABS224

Anti-YVH1 Antibody

from rabbit, purified by affinity chromatography

• Sinonimo/i: Dual specificity protein phosphatase 12, Dual specificity tyrosine phosphatase YVH1
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Purificato mediante: affinity chromatography
• Reattività contro le specie: human
• tecniche: western blot: suitable
• N° accesso NCBI: NP_009171
• N° accesso UniProt: Q9UNI6
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... DUSP12(11266)

Descrizione

Descrizione generale

Yeast VH1-related phosphatase (YVH1), also known as “dual specificity protein phosphatase 12” (DUSP12) is a ubiquitous phosphatase, with relatively high levels of expression in the ovary, testis, spleen, and peripheral blood leukocytes. YVH1 primarily removes phosphate groups from phosphorylated serine, threonine, and tyrosine residues in its target substrates. However, YVH1 also contains a zinc-binding domain which may enable it to interact with other proteins involved in cell growth, cell survival, and cell cycle progression. YVH1 may also be involved in the assembly of ribosomes, and in the biogenesis of the 60S ribosomal subunit. It can be targeted to different subcellular locations by phosphorylation of its Ser335 residue located in the zinc-binding domain.

Immunogeno

GST-tagged recombinant protein corresponding to human YVH1.

Applicazioni

Anti-YVH1 Antibody is an antibody against YVH1 for use in Western Blotting.

Research Category
Signaling

Research Sub Category
Kinases & Phosphatases

Western Blot Analysis: A representative lot detected YVH1 in 10 µg of Jurkat cell lysate.

Qualità

Evaluated by Western Blot in HeLa cells.

Western Blot Analysis: A 1:500 dilution of this antibody detected YVH1 in 10 µg of HeLa cell lysate.

Descrizione del bersaglio

~38 kDa observed. An uncharacterized band at ~36 kDa may be observed in some cell lysates.

Stato fisico

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Risultati analitici

Control
HeLa cells

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable