Reattività contro le specie (prevista in base all’omologia)
all
Produttore/marchio commerciale
Upstate®
tecniche
immunocytochemistry: suitable
Condizioni di spedizione
wet ice
modifica post-traduzionali bersaglio
phosphorylation (pSer/pThr)
Descrizione generale
This antibody recognizes a variety of proteins that are phosphorylated during mitosis.
Anti-phospho-Ser/Thr-Pro, MPM-2 (05-368) conjugated to fluorescein-5-EX, succinimidyl ester (FSE)
Applicazioni
Detect phospho-Ser/Thr-Pro also known as Mitotic protein #2 with Anti-phospho-Ser/Thr-Pro Antibody, MPM-2, FITC conjugate (Mouse Monoclonal Antibody), that has been demonstrated to work in ICC.
For applications in which an FITC conjugate is advantageous, such as ICC.
Research Category Epigenetics & Nuclear Function
Research Sub Category Cell Cycle, DNA Replication & Repair
Qualità
routinely evaluated in immunocytochemistry on A431 mitotic cells fixed with 3.7% paraformaldehyde
Stato fisico
TBS, pH 8.0, 0.05% sodium azide and 30% glycerol
Stoccaggio e stabilità
Stable for 1 year at -20°C from date of shipment. Store in the dark. For maximum recovery of product, centrifuge the vial.
Note legali
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Non trovi il prodotto giusto?
Prova il nostro Motore di ricerca dei prodotti.
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
Possiedi già questo prodotto?
I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships.
Timothy R Rudd,Katarzyna A Uniewicz,Alessandro Ori,Scott E Guimond,Mark A Skidmore et al.
MYC proteins are major drivers of cancer yet are considered undruggable because their DNA binding domains are composed of two extended alpha helices with no apparent surfaces for small-molecule binding. Proteolytic degradation of MYCN protein is regulated in part by
cdc25 is one of the MPM-2 antigens involved in the activation of maturation-promoting factor.
Kuang, J, et al.
Molecular Biology of the Cell, 5, 135-145 (1994)
Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism.
Yaffe, M B, et al.
Science (New York, N.Y.), 278, 1957-1960 (1997)
A small-molecule inhibitor targeting the mitotic spindle checkpoint impairs the growth of uterine leiomyosarcoma.
Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..