14-845-M
PIP5K1γ Protein, active, 10 µg
Active, N-terminal 6His-tagged, recombinant human PIP5K1γ, full length. For use in Kinase Assays.
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10 μG
985,00 €
250 μG
3.410,00 €
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Cambia visualizzazione
10 μG
985,00 €
250 μG
3.410,00 €
About This Item
Codice UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.41
Prodotti consigliati
Origine biologica
human
Livello qualitativo
Ricombinante
expressed in baculovirus infected Sf21 cells
PM
Mw 77 kDa
Produttore/marchio commerciale
Upstate®
tecniche
activity assay: suitable (kinase)
N° accesso NCBI
N° accesso UniProt
Informazioni sul gene
human ... PIP5K1C(23396)
Descrizione generale
N-terminal 6His-tagged, recombinant human PIP5K1γ, full length.
Product Source: Expressed by baculovirus in Sf21 insect cells
Applicazioni
Active, N-terminal 6His-tagged, recombinant human PIP5K1γ, full length. For use in Kinase Assays.
Research Category
Signaling
Signaling
Research Sub Category
Oncology
Inflammation & Autoimmune Mechanisms
Diabetes
Alzheimer′s Disease
Neurodegenerative Diseases
Oncology
Inflammation & Autoimmune Mechanisms
Diabetes
Alzheimer′s Disease
Neurodegenerative Diseases
Azioni biochim/fisiol
Protein Target: PIP5K1γ
Target Sub-Family: PIPK
Confezionamento
Also available in 250μg size as catalog # 14-845M - Call for pricing and availability.
Qualità
Routinely evaluated in the PIProfiler.
Stato fisico
10µg of enzyme in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 0.2mM PMSF, 1mM benzamidine, 0.1% 2-mercaptoethanol. Frozen solution.
Immobilized metal affinity chromatography (IMAC)
Stoccaggio e stabilità
6 months at -70°C
Altre note
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Note legali
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Development of a High-Throughput Screening Assay to Identify Inhibitors of the Lipid Kinase PIP5K1C.
Brittany D Wright et al.
Journal of biomolecular screening, 20(5), 655-662 (2014-12-24)
Phosphatidylinositol 4-phosphate 5-kinases (PIP5Ks) regulate a variety of cellular processes, including signaling through G protein-coupled receptors (GPCRs), endocytosis, exocytosis, and cell migration. These lipid kinases synthesize phosphatidylinositol 4,5-bisphosphate (PIP2) from phosphatidylinositol 4-phosphate [PI(4)P]. Because small-molecule inhibitors of these lipid kinases
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