14-700

NEK11 Protein, active, 10 µg

• Codice UNSPSC: 12352202
• eCl@ss: 32160405

Proprietà

• Ricombinante: expressed in baculovirus infected Sf21 cells
• Livello qualitativo: 100
• Descrizione: protein target NEK11
• Purificato mediante: (Ni²⁺/NTA-agarose)
• tecniche: activity assay: suitable
• N° accesso UniProt: Q8NG66
• Informazioni sul gene: human ... NEK11(79858)

Descrizione

Descrizione generale

FUNCTION: SwissProt: Q8NG66 # Possible role in S-phase checkpoint mechanism.
COFACTOR: Manganese or magnesium.
SIZE: 645 amino acids; 74162 Da
SUBCELLULAR LOCATION: Nucleus. Nucleus, nucleolus. Note=Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase. Accumulates in the nucleolus in G1/S- arrested cells.
TISSUE SPECIFICITY: Poorly expressed in cerebellum, trachea, lung, appendix, and uterus.
DEVELOPMENTAL STAGE: Predominantly expressed at S/G2/M phase.
PTM: Phosphorylated.
SIMILARITY: SwissProt: Q8NG66 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. NIMA subfamily. & Contains 1 protein kinase domain.

Qualità

routinely evaluated by phosphorylation of MBP (Catalog # 13-104)

Proprietà fisiche

59.3kDa

Stoccaggio e stabilità

6 months at -70°C from date of shipment

Risultati analitici

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H317
• Consigli di prudenza: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Classi di pericolo: Skin Sens. 1
• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable