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04-080

Anti-BAF250a/ARID1a Antibody, clone PSG3

clone PSG3, Upstate®, from mouse

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Informazioni su questo articolo

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
PSG3, monoclonal
Application:
IF, WB
Citations:
19
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

PSG3, monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunofluorescence: suitable, western blot: suitable

isotype

IgG

General description

~270 kDa

Immunogen

GST fusion protein corresponding to 419 residues in the mid-portion of human BAF250a/ARID1a

Application

Anti-BAF250a/ARID1a Antibody, clone PSG3 is an antibody against BAF250a/ARID1a for use in WB, ChIP, IC & IHC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Chromatin Biology

Transcription Factors

Biochem/physiol Actions

BAF250a/ARID1a

Physical form

100 μg of Protein A purified mouse monoclonal IgG in 100μl of 1X PBS, pH 7.0, 0.1% Azide.
Format: Purified
Protein A purified

Preparation Note

2 years at -20°C from date of shipment

Analysis Note

Routinely evaluated by immunoblot.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Descrizione
Determinazione del prezzo

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Classe di stoccaggio

12 - Non Combustible Liquids


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Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling.
Chandler, RL; Damrauer, JS; Raab, JR; Schisler, JC; Wilkerson, MD; Didion, JP; Starmer et al.
Nature Communications null
Hiroko Inoue et al.
The Journal of biological chemistry, 277(44), 41674-41685 (2002-08-30)
The mammalian SWI/SNF-related complexes facilitate gene transcription by remodeling chromatin using the energy of ATP hydrolysis. The recruitment of these complexes to promoters remains poorly understood and may involve histone modifications or direct interactions with site-specific transcription factors or other
Essential role of ARID2 protein-containing SWI/SNF complex in tissue-specific gene expression.
Xu, F; Flowers, S; Moran, E
The Journal of Biological Chemistry null
Radhika Mathur et al.
Nature genetics, 49(2), 296-302 (2016-12-13)
Genes encoding subunits of SWI/SNF (BAF) chromatin-remodeling complexes are collectively mutated in ∼20% of all human cancers. Although ARID1A is the most frequent target of mutations, the mechanism by which its inactivation promotes tumorigenesis is unclear. Here we demonstrate that
Xiaomei Wang et al.
The Biochemical journal, 383(Pt 2), 319-325 (2004-06-02)
p270 (ARID1A) is a member of the ARID family of DNA-binding proteins and a subunit of human SWI/SNF-related complexes, which use the energy generated by an integral ATPase subunit to remodel chromatin. ARID1B is an independent gene product with an

Numero articolo commerciale globale

SKUGTIN
04-08004053252669422

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