L-027

Lacosamide-¹³C, D₃ solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Formula empirica (notazione di Hill): ¹³CC₁₂D₃H₁₅N₂O₃
• Peso molecolare: 254.30
• Numero CE: 200-835-2
• Codice UNSPSC: 41116107
• NACRES: NA.24

Proprietà

• Grado: certified reference material
• Forma fisica: liquid
• Caratteristiche: Snap-N-Spike^®/Snap-N-Shoot^®
• Confezionamento: ampule of 1 mL
• Produttore/marchio commerciale: Cerilliant^®
• Concentrazione: 100 μg/mL in acetonitrile
• tecniche: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• applicazioni: clinical testing
• Formato: single component solution
• Temperatura di conservazione: −20°C
• Stringa SMILE: [2H][13C]([2H])([2H])OC[C@@H](NC(C)=O)C(=O)NCc1ccccc1
• InChI: 1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1/i2+1D3; VPPJLAIAVCUEMN-RUXIMPAMSA-N

Descrizione

Descrizione generale

Lacosamide is a new antiepileptic drug approved by the FDA in late 2008 for the treatment of partial-onset seizures and diabetic neuropathic pain. The drug is marketed under the trade name Vimpat^®. This internal standard is suitable for lacosamide testing methods by LC/MS or GC/MS for clinical toxicology, forensic analysis, or urine drug testing.

Applicazioni

• Lacosamide-¹³C,D₃ in Pharmacokinetic Research: A study employed Lacosamide-¹³C,D₃ in a selective quantification method using UPLC-MS/MS, focusing on its pharmacokinetic profiles in healthy subjects. This research underscores the utility of stable isotope-labeled Lacosamide in assessing drug metabolism and distribution, crucial for optimizing therapeutic dosages and improving drug safety profiles (Bharwad et al., 2020).

Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Vimpat is a registered trademark of Harris FRC Corporation

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H225,H302 + H312 + H332,H319
• Consigli di prudenza: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): 35.6 °F - closed cup
• Punto d’infiammabilità (°C): 2 °C - closed cup