D-088

N-Desmethylcyclobenzaprine hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• Formula empirica (notazione di Hill): C₁₉H₁₉N · HCl
• Numero CAS: 438-59-5
• Peso molecolare: 297.82
• Numero MDL: MFCD01731061
• Codice UNSPSC: 41116107
• ID PubChem: 329798646
• NACRES: NA.24

Proprietà

• Grado: certified reference material
• Livello qualitativo: 300
• Stato: liquid
• Caratteristiche: (Snap-N-Spike^®)
• Confezionamento: ampule of 1 mL
• Produttore/marchio commerciale: Cerilliant^®
• Concentrazione: 1.0 mg/mL in methanol (as free base)
• tecniche: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• applicazioni: clinical testing
• Formato: single component solution
• Temperatura di conservazione: −20°C
• Stringa SMILE: CNCCC=C1C2=C(C=CC=C2)C=CC3=C1C=CC=C3.Cl
• InChI: 1S/C19H19N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-13,20H,6,14H2,1H3;1H; UZMPCPFDZYTEJG-UHFFFAOYSA-N

Descrizione

Descrizione generale

A certified Snap-N-Spike^® Solution suitable for cyclobenzaprine testing methods by GC/MS or LC/MS for applications in pain prescription monitoring, forensic analysis, urine drug testing, or clinical toxicology. Also known as norcyclobenzaprine, N-desmethylcyclobenzaprine is the major urinary metabolite of the skeletal muscle relaxant cyclobenzaprine. Cyclobenzaprine, sold under trade names Flexeril^®, Fexmid^®, and Amrix^®, is used to relieve skeletal muscle spasms and associated pain from acute musculoskeletal conditions.

Applicazioni

• Formation of Mammalian Metabolites of Cyclobenzaprine: Research demonstrated that the fungus Cunninghamella elegans could produce mammalian metabolites of cyclobenzaprine, including N-Desmethylcyclobenzaprine. This study highlights the potential use of microbial models in pharmacokinetic studies to simulate and study drug metabolism pathways, providing a cost-effective and simpler alternative to traditional in vivo metabolic studies (Zhang et al., 1996).

Note legali

Amrix is a registered trademark of Ivax International GMBH LLC

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Fexmid is a registered trademark of Shionogi Inc.

Flexeril is a registered trademark of ALZA Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS06,GHS08,GHS09
• Avvertenze: Danger
• Indicazioni di pericolo: H225,H301 + H311 + H331,H370,H411
• Consigli di prudenza: P210 - P273 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Classi di pericolo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Flam. Liq. 2 - STOT SE 1
• Organi bersaglio: Eyes
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 49.5 °F
• Punto d’infiammabilità (°C): 9.7 °C