850755C

18:2 PE

1,2-dilinoleoyl-sn-glycero-3-phosphoethanolamine, chloroform

• Sinonimo/i: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine; PE(18:2(9Z,12Z)/18:2(9Z,12Z))
• Formula empirica (notazione di Hill): C₄₁H₇₄NO₈P
• Numero CAS: 20707-71-5
• Peso molecolare: 740.00
• Codice UNSPSC: 51191904
• NACRES: NA.25

Proprietà

• Saggio: >99% (TLC)
• Stato: liquid
• Confezionamento: pkg of 1 × 2.5 mL (850755C-25mg); pkg of 2 × 4 mL (850755C-200mg)
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand 850755C
• Concentrazione: 10 mg/mL (850755C-25mg); 25 mg/mL (850755C-200mg)
• Tipo di lipide: cardiolipins; phospholipids
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• Stringa SMILE: [H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCC/C=C\C/C=C\CCCCC)=O
• InChI: 1S/C41H74NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h11-14,17-20,39H,3-10,15-16,21-38,42H2,1-2H3,(H,45,46)/b13-11-,14-12-,19-17-,20-18-/t39-/m1/s1; SSCDRSKJTAQNNB-DWEQTYCFSA-N

Descrizione

Descrizione generale

Phosphatidylethanolamine (PE) is the second most plenteous glycerophospholipid in eukaryotic cells.[1] It is a non-bilayer forming phospholipid, which is found majorly in the mitochondria.[2] It consists of a small polar head group with fatty acid chains.[1]

Applicazioni

18:2 PE has been used for the preparation of liposomes.[3]

Azioni biochim/fisiol

Phosphatidylethanolamine (PE) functions as to provide rigidity to the cell membranes via hexagonal phase structures which promote tight packing of the membrane bilayer formed by phosphatidylcholine.[1] It is also involved in the conversion of prions from the non-toxic to toxic conformation. PE also initiates the autophagosome formation by attaching covalently to the autophagy Atg8 protein.[2]

Confezionamento

5 mL Clear Glass Sealed Ampule (850755C-200mg)

5 mL Clear Glass Sealed Ampule (850755C-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H315,H319,H331,H336,H351,H361d,H372
• Consigli di prudenza: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Classi di pericolo: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Organi bersaglio: Liver,Kidney, Respiratory system
• Codice della classe di stoccaggio: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): does not flash
• Punto d’infiammabilità (°C): does not flash