481408

Chlorodicyclohexylphosphine

97%

• Sinonimo/i: Dicyclohexylchlorophosphine, Dicyclohexylphosphine chloride, Dicyclohexylphosphinous chloride
• Formula condensata: (C₆H₁₁)₂PCl
• Numero CAS: 16523-54-9
• Peso molecolare: 232.73
• Numero MDL: MFCD00014294
• Codice UNSPSC: 12352101
• ID PubChem: 24871756
• NACRES: NA.22

Proprietà

• Livello qualitativo: 100
• Saggio: 97%
• Impiego in reazioni chimiche: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• Indice di rifrazione: n20/D 1.533 (lit.)
• P. ebollizione: 165 °C/12 mmHg (lit.)
• Densità: 1.054 g/mL at 25 °C (lit.)
• Gruppo funzionale: phosphine
• Stringa SMILE: ClP(C1CCCCC1)C2CCCCC2
• InChI: 1S/C12H22ClP/c13-14(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h11-12H,1-10H2; AKJFBIZAEPTXIL-UHFFFAOYSA-N

Descrizione

Applicazioni

Chlorodicyclohexylphosphine can be used as a reactant in the synthesis of:

• 1,2-Bis(dicyclohexylphosphinoxy)ethane ligand by reacting with ethylene glycol in the presence of triethylamine via Michaelis−Arbuzov type rearrangements.[1]
• 1,1,2,2-tetracyclohexyldiphosphine monosulfide ligand by treating with LiS.[2]

It can be also used as a starting material for the preparation of some other ligands such as dicyclohexylphosphine oxide [3], phosphino substituted N-aryl pyrroles [4], di-tert-butyl((dicyclohexylphosphino)methyl)phosphine [5], dicyclohexylcyclopentylphosphine[6]. These ligands are used in Pd-catalyzed cross-coupling reactions.

Informazioni sulla sicurezza

• Pittogrammi: GHS05
• Avvertenze: Danger
• Indicazioni di pericolo: H314
• Consigli di prudenza: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Classi di pericolo: Eye Dam. 1 - Skin Corr. 1B
• Rischi supp: EUH014
• Codice della classe di stoccaggio: 8A - Combustible corrosive hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 235.4 °F - closed cup
• Punto d’infiammabilità (°C): 113 °C - closed cup
• Dispositivi di protezione individuale: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter