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421669

Sigma-Aldrich

Asp-Phe

96%, for peptide synthesis

Sinonimo/i:

L-Aspartyl-L-phenylalanine, Aspartame acid

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About This Item

Formula condensata:
HOOCCH2CH(NH2)CONHCH(CH2C6H5)CO2H
Numero CAS:
Peso molecolare:
280.28
Beilstein:
2817528
Numero CE:
Numero MDL:
Codice UNSPSC:
12352209
ID PubChem:
NACRES:
NA.22

product name

Asp-Phe, 96%

Saggio

96%

Forma fisica

powder

Attività ottica

[α]20/D +12.5°, c = 1 in 0.5 M HCl

Impiego in reazioni chimiche

reaction type: solution phase peptide synthesis

Punto di fusione

236-239 °C (lit.)

applicazioni

peptide synthesis

Stringa SMILE

N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI

1S/C13H16N2O5/c14-9(7-11(16)17)12(18)15-10(13(19)20)6-8-4-2-1-3-5-8/h1-5,9-10H,6-7,14H2,(H,15,18)(H,16,17)(H,19,20)/t9-,10-/m0/s1
YZQCXOFQZKCETR-UWVGGRQHSA-N

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Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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L-Phenylalanine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1100

L-Phenylalanine

Aspartame United States Pharmacopeia (USP) Reference Standard

USP

1043706

Aspartame

Aspartame analytical standard

Supelco

47135

Aspartame

Methyl myristate analytical standard

Supelco

70129

Methyl myristate

L-Phenylalanine BioUltra, ≥99.0% (NT)

Sigma-Aldrich

78019

L-Phenylalanine

E G Burton et al.
The Journal of nutrition, 119(5), 713-721 (1989-05-01)
A new beta-aspartyl dipeptide, N-beta-L-aspartyl-L-phenylalanine (beta-AP), has been isolated and identified in urine and plasma from normal human volunteers. beta-AP was isolated from urine samples by high performance liquid chromatography (HPLC). Its identity and stereochemistry were demonstrated by HPLC and
N A Tobey et al.
Gastroenterology, 91(4), 931-937 (1986-10-01)
Aspartame [Nutrasweet, Equal (Searle Consumer Products, Chicago, Ill.)] is the methyl ester of the dipeptide aspartylphenylalanine (Asp-Phe). After hydrolysis of the ester bond in the intestinal lumen, the dipeptide is apparently absorbed and digested in the same manner as dipeptides
S S Leung et al.
Journal of pharmaceutical sciences, 86(1), 64-71 (1997-01-01)
Some solid-state pharmaceutical properties and the solid-state thermal stability of the model dipeptides aspartame (APM) and aspartylphenylalanine (AP), have been investigated. Studies by differential scanning calorimetry (DSC), thermal gravimetric analysis (TGA), high-performance liquid chromatography, powder X-ray diffraction, and optical microscopy
Y In et al.
Chemical & pharmaceutical bulletin, 48(3), 374-381 (2000-03-22)
As part of the series investigating the structural features of C-terminal amidated amino acids and peptides, three crystal structures of Z-Gly-Phe-NH2, Tyr-Lys-NH2, and Asp-Phe-NH2 were analyzed by the X-ray diffraction method, and their molecular conformations and intermolecular interactions were investigated.
Montserrat Andújar-Sánchez et al.
FEBS letters, 581(18), 3449-3454 (2007-07-10)
Somatic angiotensin I-converting enzyme (s-ACE) plays a central role in blood pressure regulation and has been the target of most antihypertensive drugs. A displacement isothermal titration calorimetry method has been used to accurately determine the binding constant of three strong

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