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399655

Sigma-Aldrich

1-Pyrenebutanol

99%

Sinonimo/i:

4-(1-Pyrenyl)butanol, 4-(Pyren-1-yl)butan-1-ol

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About This Item

Formula empirica (notazione di Hill):
C20H18O
Numero CAS:
67000-89-9
Peso molecolare:
274.36
Numero MDL:
MFCD00192423
Codice UNSPSC:
12352100
ID PubChem:
24864832
NACRES:
NA.22

Saggio

99%

Punto di fusione

80-83 °C (lit.)

Stringa SMILE

OCCCCc1ccc2ccc3cccc4ccc1c2c34

InChI

1S/C20H18O/c21-13-2-1-4-14-7-8-17-10-9-15-5-3-6-16-11-12-18(14)20(17)19(15)16/h3,5-12,21H,1-2,4,13H2
MRENSFROWALQNU-UHFFFAOYSA-N

Categorie correlate

Descrizione generale

1-Pyrenebutanol, an alcohol, is an organic building block. It participates in the polymerization of cyclic esters (lactide, δ-valerolactone and ε-caprolactone).

Applicazioni

1-Pyrenebutanol may be employed in the following studies:
  • As a new fluorescent substrate to investigate the allosteric mechanism of P450eryF.
  • Preparation of fluorescent polymer based on D,L-lactic acid units end-capped with 1-pyrenebutanol by ring-opening polymerization.
  • Synthesis of 1-pyrenebutanol (PB)-labeled poly(lactic acid) (PLA) nanoparticles (NPs).

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Dmitri R Davydov et al.
Biochemical and biophysical research communications, 294(4), 806-812 (2002-06-14)
1-Pyrenebutanol (1-PB) has been used as a new fluorescent substrate for P450eryF to explore the molecular mechanisms of cooperativity. Hydroxylation of 1-PB by P450eryF was detected by both fluorometric and chromatographic assays. Binding was monitored by a substrate-induced low-to-high spin
Poly (L-lactide) Nanoparticles via Ring-Opening Polymerization in Non-aqueous Emulsion.
Dorresteijn R, et al.
Macromolecular Chemistry and Physics, 213(19), 1996-2002 (2012)
Cung An Nguyen et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 20(2), 217-222 (2003-10-11)
A new fluorescent polymer based on D,L-lactic acid units end-capped with 1-pyrenebutanol (PLAP) was synthesized by ring-opening polymerization. PLAP having different molecular weight could be obtained by varying the ratio of D,L-lactide and 1-pyrenebutanol. Fluorescent nanoparticles (NP) were prepared using
Kazuki Fukushima et al.
Biomacromolecules, 18(11), 3834-3843 (2017-10-04)
We developed a biodegradable polycarbonate that demonstrates antithrombogenicity and vascular cell adhesion via organocatalytic ring-opening polymerization of a trimethylene carbonate (TMC) analogue bearing a methoxy group. The monoether-tagged polycarbonate demonstrates a platelet adhesion property that is 93 and 89% lower
Dane Christie et al.
ACS central science, 4(4), 504-511 (2018-05-04)
Nanoscale compositional heterogeneity in block copolymers can impart synergistic property combinations, such as stiffness and toughness. However, until now, there has been no experimental method to locally probe the dynamics at a specific location within these structured materials. Here, this
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