Passa al contenuto
Merck
Tutte le immagini(1)

Documenti

10879

Sigma-Aldrich

1,1,3-Trichloroacetone

produced by Wacker Chemie AG, Burghausen, Germany, ≥86.5% (GC)

Sinonimo/i:

TCA, 1,1,3-Trichloro-2-propanone

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(1)

About This Item

Formula condensata:
(Cl)2CHCOCH2Cl
Numero CAS:
921-03-9
Peso molecolare:
161.41
Beilstein:
1746647
Numero MDL:
MFCD00040500
Codice UNSPSC:
12352100
ID PubChem:
57646825
NACRES:
NA.22

Grado

produced by Wacker Chemie AG, Burghausen, Germany

Saggio

≥86.5% (GC)

P. eboll.

88-90 °C/76 mmHg (lit.)

Punto di fusione

9-11 °C (lit.)

Densità

1.512 g/mL at 20 °C (lit.)

Stringa SMILE

ClCC(=O)C(Cl)Cl

InChI

1S/C3H3Cl3O/c4-1-2(7)3(5)6/h3H,1H2
ZWILTCXCTVMANU-UHFFFAOYSA-N

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Categorie correlate

Descrizione generale

1,1,3-Trichloroacetone is direct-acting mutagens in the Ames/Salmonella assay. It is precursor for the generation of 1,3-dihalo oxyallyl intermediates, which undergo [4 + 3] cycloadditions with a host of 1,3-diene systems.

Applicazioni

1,1,3-Trichloroacetone was used in base-induced solvolyses of [3.2.1]Bicyclic α,α′-dichloro ketones.

Altre note

prices for bulk quantities on request

Avvertenze

Danger

Indicazioni di pericolo

H301 + H311,H314,H330,H410

Classi di pericolo

Acute Tox. 1 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

W F Blazak et al.
Mutation research, 206(4), 431-438 (1988-12-01)
1,1,1- and 1,1,3-trichloroacetones (TCA) result from the disinfection of municipal water supplies with chlorine, and are direct-acting mutagens in the Ames/Salmonella assay. The objective of this study was to further investigate the genotoxicity of these compounds in mammalian cells using
Ho Lam Chan et al.
Nature communications, 9(1), 3377-3377 (2018-08-25)
Polycomb repressive complex 1 (PRC1) plays essential roles in cell fate decisions and development. However, its role in cancer is less well understood. Here, we show that RNF2, encoding RING1B, and canonical PRC1 (cPRC1) genes are overexpressed in breast cancer.
Base-Induced Solvolyses of [3.2. 1] Bicyclic a, a'-Dichloro Ketones- 1, 3-Transposition and Ring-Contraction.
Fohlisch B, et al.
European Journal of Organic Chemistry, 2001(22), 4357-4365 (2001)
Yusheng Zhang et al.
Science advances, 6(23), eaaz7249-eaaz7249 (2020-06-18)
RING1B, a core Polycomb repressive complex 1 subunit, is a histone H2A ubiquitin ligase essential for development. RING1B is overexpressed in patients with luminal breast cancer (BC) and recruited to actively transcribed genes and enhancers co-occupied by the estrogen receptor
M Robinson et al.
Cancer letters, 48(3), 197-203 (1989-12-01)
Several chlorinated acetones have been identified in drinking water and these, as well as a number of chlorinated acroleins, are produced by chlorination of humic acid solutions. Many of these chlorinated compounds and the brominated acrolein analog were positive in
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.