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106305

Sigma-Aldrich

Nitrilotriacetic acid trisodium salt monohydrate

≥99%

Sinonimo/i:

Sodium nitrilotriacetate tribasic monohydrate

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About This Item

Formula condensata:
N(CH2COONa)3 · H2O
Numero CAS:
18662-53-8
Peso molecolare:
275.10
Numero CE:
225-768-6
Numero MDL:
MFCD00150789
Codice UNSPSC:
12352100
ID PubChem:
24846729

Saggio

≥99%

Punto di fusione

>300 °C (lit.)

Stringa SMILE

O.[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CC([O-])=O

InChI

1S/C6H9NO6.3Na.H2O/c8-4(9)1-7(2-5(10)11)3-6(12)13;;;;/h1-3H2,(H,8,9)(H,10,11)(H,12,13);;;;1H2/q;3*+1;/p-3
HERBOKBJKVUALN-UHFFFAOYSA-K

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Applicazioni

Nitrilotriacetic acid trisodium salt monohydrate was used to develop capillary zone electrophoretic method for determination of eight carboxylates as copper complexes.

Azioni biochim/fisiol

Nitrilotriacetic acid trisodium salt monohydrate is a potent nongenotoxic carcinogen and has induced tumors of the urinary bladder and kidney on long term administration in rats. It induces diphtheria toxin-resistant mutants in human cell lines. It inhibits gap-junctional communication between chinese hamster lung fibroblast.

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Pittogrammi

Health hazardExclamation mark
GHS08,GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302,H319,H351

Classi di pericolo

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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A R Malcolm et al.
Cell biology and toxicology, 5(2), 145-153 (1989-06-01)
Di(2-ethylhexyl)phthalate and trisodium nitrilotriacetate monohydrate, two apparently nongenotoxic carcinogens, were tested for effects on gap-junctional communication between Chinese hamster V79 lung fibroblasts. Both compounds inhibited gap-junctional communication in a concentration-dependent manner. The inhibiting effects of these chemicals on gap-junctional communication
Pirkko-Leena Laamanen et al.
Journal of chromatography. A, 1095(1-2), 164-171 (2005-11-09)
Two new methods of capillary zone electrophoresis based on aqueous phosphate running buffers with UV spectrophotometric detection were developed and optimized for the determination of eight carboxylates as copper complexes. Metalcomplexes are negatively charged, so measurements were made as anion
M P Grilli et al.
Toxicology letters, 25(2), 137-141 (1985-05-01)
The mutagenic potential of nitrilotriacetic acid trisodium salt monohydrate (NTA) was evaluated on a human cell line (EUE) using selection for diphtheria toxin (DT) resistance. Cultures were treated with different doses of the chemical (2 X 10(-2)-2 X 10(-8) M)
S Inoue et al.
Cancer research, 47(24 Pt 1), 6522-6527 (1987-12-15)
Reactivities of Fe3+ chelates of aminopolycarboxylic acids with DNA were investigated by the DNA-sequencing technique using 32P 5'-end-labeled DNA fragments obtained from the human c-Ha-ras-1 protooncogene, and the reaction mechanism was studied by electron spin resonance spectroscopy. Ferric nitrilotriacetate (Fe3+-NTA)

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