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Merck

THRB

thyroid hormone receptor, beta

Sinonimi:
C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2
Specie:
ID UniProtKB:
ID gene:
  • Human(7068) Summary: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(21834) thyroid hormone receptor beta
  • Rat(24831) thyroid hormone receptor beta
  • Domestic Rabbit(100303763) thyroid hormone receptor, beta
  • chicken(396431) thyroid hormone receptor, beta
  • cow(788329) thyroid hormone receptor, beta
  • domestic cat(101084821) thyroid hormone receptor, beta
  • Horse(100051615) thyroid hormone receptor, beta
  • dog(403599) thyroid hormone receptor, beta
  • naked mole-rat(101719651) thyroid hormone receptor, beta
  • domestic guinea pig(100721125) thyroid hormone receptor, beta
  • Zebrafish(30607) thyroid hormone receptor beta

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
3,3′,5-Triiodo-L-thyronine (T3) solution, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
L-Thyroxine (T4) solution, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Levothyroxine, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Levothyroxine sodium, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Liothyronine, United States Pharmacopeia (USP) Reference Standard,
Specie
human

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
3,3′,5-Triiodo-L-thyronine sodium salt, powder, BioReagent, suitable for cell culture,
Specie
rat, human
3,3′,5-Triiodo-L-thyronine, ≥95% (HPLC), powder,
Specie
rat, human
3,3′,5-Triiodo-L-thyronine sodium salt, γ-irradiated, powder, suitable for, suitable for cell culture,
Specie
rat, human
3,3′,5-Triiodothyroacetic acid, ≥90%,
Specie
rat, human
L-Thyroxine, ≥98% (HPLC),
Specie
human, mouse, rat

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Thyroid Hormone Receptor β-1 Antibody, from rabbit, purified by affinity chromatography,
Reattività con
human, mouse, rat
Applicazione
western blot
Anti-Thyroid Hormone Receptor β, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry

western blot
Anti-THRB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-THRB antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
canine, human, mouse, rat
Applicazione
ELISA
western blot
Anti-phospho-TR-β1 (pSer142) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
3,3′,5-Triiodo-L-thyronine sodium salt, powder, BioReagent, suitable for cell culture,
Specie
rat, human
3,3′,5-Triiodo-L-thyronine, ≥95% (HPLC), powder,
Specie
rat, human
3,3′,5-Triiodo-L-thyronine sodium salt, γ-irradiated, powder, suitable for, suitable for cell culture,
Specie
rat, human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human THRB,
Specie
human